Evidence map›Paper›PMID 37243231›Full record

ArticleViruses2023

Cytokine Response Following SARS-CoV-2 Antigen Stimulation in Patients with Predominantly Antibody Deficiencies.

Zane Lucane, Baiba Slisere, Gita Gersone, Sindija Papirte, Linda Gailite, Peteris Tretjakovs, Natalja Kurjane

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zane LucaneDepartment of Biology and Microbiology, Riga Stradins University, LV-1007 Riga, Latvia.
Baiba SlisereThe Joint Laboratory, Pauls Stradins Clinical University Hospital, LV-1002 Riga, Latvia.
Gita GersoneDepartment of Human Physiology and Biochemistry, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0003-2228-4713
Sindija PapirteFaculty of Medicine, Riga Stradins University, LV-1007 Riga, Latvia.
Linda GailiteScientific Laboratory of Molecular Genetics, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0002-7219-1294
Peteris TretjakovsDepartment of Human Physiology and Biochemistry, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0001-9446-0558
Natalja KurjaneDepartment of Biology and Microbiology, Riga Stradins University, LV-1007 Riga, Latvia.
Riga Stradiņš University · LVPauls Stradiņš Clinical University Hospital · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predominantly antibody deficiencies (PADs) are inborn disorders characterized by immune dysregulation and increased susceptibility to infections. Response to vaccination, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may be impaired in these patients, and studies on responsiveness correlates, including cytokine signatures to antigen stimulation, are sparse. In this study, we aimed to describe the spike-specific cytokine response following whole-blood stimulation with SARS-CoV-2 spike peptides in patients with PAD (

Indexed as

COVID-19Immunologic Deficiency SyndromesAntibodies, ViralCytokinesHumansImmunoglobulin GSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, ViralCytokinesImmunoglobulin GSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibody deficiencycommon variable immunodeficiencyCOVID-19cytokineSARS-CoV-2selective IgA deficiency

Identifiers

PMID37243231
PMCPMC10222647
OpenAlexW4378516082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.