Evidence map›Paper›PMID 37243062›Full record

ArticleVaccines2023

SARS-CoV-2 Vaccine Breakthrough Infections of Omicron and Delta Variants in Healthcare Workers.

Elisa Regenhardt, Holger Kirsten, Melanie Weiss, Christoph Lübbert, Sebastian N Stehr, Yvonne Remane, Corinna Pietsch, Mario Hönemann, Amrei von Braun

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Anti-SARS-CoV-2 Antibody Levels in a Cohort of Health Care Workers Before and After the Omicron Wave in Canada.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Elisa RegenhardtDivision of Infectious Diseases and Tropical Medicine, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0009-0009-4426-2874
Holger KirstenInstitute for Medical Informatics, Statistics, and Epidemiology, University of Leipzig, 04107 Leipzig, Germany.ORCID 0000-0002-3126-7950
Melanie WeissCentral Institution for Occupational Medicine and Occupational Safety, Leipzig University Medical Center, 04103 Leipzig, Germany.
Christoph LübbertDivision of Infectious Diseases and Tropical Medicine, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0001-6942-5785
Sebastian N StehrDepartment of Anaesthesiology and Critical Care Medicine, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0003-0635-5112
Yvonne RemaneCentral Pharmacy, Leipzig University Medical Center, 04103 Leipzig, Germany.
Corinna PietschInterdisciplinary Center for Infectious Diseases (ZINF), Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0001-6029-3368
Mario HönemannInterdisciplinary Center for Infectious Diseases (ZINF), Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0001-7517-402X
Amrei von BraunDivision of Infectious Diseases and Tropical Medicine, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-4335-8884
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding SARS-CoV-2 breakthrough infections in vaccinated healthcare workers is of key importance in mitigating the effects of the COVID-19 pandemic in healthcare facilities. An observational prospective cohort study was conducted in vaccinated employees with acute SARS-CoV-2 infection between October 2021 and February 2022. Serological and molecular testing was performed to determine SARS-CoV-2 viral load, lineage, antibody levels, and neutralizing antibody titers. A total of 571 (9.7%) employees experienced SARS-CoV-2 breakthrough infections during the enrolment period, of which 81 were included. The majority (

Indexed as

breakthrough infectionDelta varianthealthcare workersOmicron variantSARS-CoV-2transmissionvaccine

Identifiers

PMID37243062
PMCPMC10220865
OpenAlexW4378515088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.