Evidence map›Paper›PMID 37243024›Full record

ArticleVaccines2023

Varying Cellular Immune Response against SARS-CoV-2 after the Booster Vaccination: A Cohort Study from Fukushima Vaccination Community Survey, Japan.

Yuta Tani, Morihito Takita, Yurie Kobashi, Masatoshi Wakui, Tianchen Zhao, Chika Yamamoto, Hiroaki Saito, Moe Kawashima, Sota Sugiura, Yoshitaka Nishikawa and 9 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Yuta TaniMedical Governance Research Institute, Tokyo 108-0074, Japan.
Morihito TakitaMedical Governance Research Institute, Tokyo 108-0074, Japan.ORCID 0000-0003-2855-4155
Yurie KobashiDepartment of Radiation Health Management, Fukushima Medical University, Fukushima 960-1295, Japan.
Masatoshi WakuiDepartment of Laboratory Medicine, Keio University School of Medicine, Tokyo 160-0016, Japan.
Tianchen ZhaoDepartment of Radiation Health Management, Fukushima Medical University, Fukushima 960-1295, Japan.
Chika YamamotoDepartment of Radiation Health Management, Fukushima Medical University, Fukushima 960-1295, Japan.
Hiroaki SaitoDepartment of Radiation Health Management, Fukushima Medical University, Fukushima 960-1295, Japan.ORCID 0000-0002-0824-454X
Moe KawashimaDepartment of Radiation Health Management, Fukushima Medical University, Fukushima 960-1295, Japan.
Sota SugiuraMedical Governance Research Institute, Tokyo 108-0074, Japan.
Yoshitaka NishikawaDepartment of General Internal Medicine, Hirata Central Hospital, Fukushima 963-8202, Japan.
Fumiya OmataDepartment of General Internal Medicine, Hirata Central Hospital, Fukushima 963-8202, Japan.
Yuzo ShimazuDepartment of General Internal Medicine, Hirata Central Hospital, Fukushima 963-8202, Japan.ORCID 0000-0002-8402-2789
Takeshi KawamuraProteomics Laboratory, Isotope Science Center, The University of Tokyo, Tokyo 113-0032, Japan.
Akira SugiyamaProteomics Laboratory, Isotope Science Center, The University of Tokyo, Tokyo 113-0032, Japan.
Aya NakayamaProteomics Laboratory, Isotope Science Center, The University of Tokyo, Tokyo 113-0032, Japan.
Yudai KanekoLaboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.
Tetsuhiko KodamaLaboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.
Masahiro KamiMedical Governance Research Institute, Tokyo 108-0074, Japan.
Masaharu TsubokuraDepartment of Radiation Health Management, Fukushima Medical University, Fukushima 960-1295, Japan.ORCID 0000-0001-8027-202X
Fukushima Medical University · JPThe University of Tokyo · JPMedical Governance Research Institute · JPKeio University · JPMedical & Biological Laboratories (Japan) · JP

Funding

Japan Agency for Medical Research and Development JP21nf0101638
6 · The paper itself

Abstract

Booster vaccination reduces the incidence of severe cases and mortality related to COVID-19, with cellular immunity playing an important role. However, little is known about the proportion of the population that has achieved cellular immunity after booster vaccination. Thus, we conducted a Fukushima cohort database and assessed humoral and cellular immunity in 2526 residents and healthcare workers in Fukushima Prefecture in Japan through continuous blood collection every 3 months from September 2021. We identified the proportion of people with induced cellular immunity after booster vaccination using the T-SPOT.COVID test, and analyzed their background characteristics. Among 1089 participants, 64.3% (700/1089) had reactive cellular immunity after booster vaccination. Multivariable analysis revealed the following independent predictors of reactive cellular immunity: age < 40 years (adjusted odds ratio: 1.81; 95% confidence interval: 1.19-2.75;

Indexed as

boostercellular immunitypopulation levelSARS-CoV-2vaccination

Identifiers

PMID37243024
PMCPMC10220831
OpenAlexW4367852293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.