Evidence map›Paper›PMID 37242996›Full record

ArticleVaccines2023

Effectiveness and Safety of Inactivated SARS-CoV-2 Vaccine (BBIBP-CorV) among Healthcare Workers: A Seven-Month Follow-Up Study at Fifteen Central Hospitals.

Rasha Ashmawy, Ehab Kamal, Wagdy Amin, Sandy Sharaf, Samar Kabeel, Raed Albiheyri, Yousra A El-Maradny, Ebtisam Hassanin, Noura Elsaka, Ola Fahmy and 8 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 3 countries.

Rasha AshmawyClinical Research Department, Maamora Chest Hospital, MoHP, Alexandria 21923, Egypt.ORCID 0000-0003-2689-5968
Ehab KamalMedical Research Division, National Research Center, Giza 12622, Egypt.
Wagdy AminGeneral Administration of Chest Diseases, MoHP, Cairo 11516, Egypt.
Sandy SharafClinical Research Department, Maamora Chest Hospital, MoHP, Alexandria 21923, Egypt.
Samar KabeelClinical Research Department, Directorate of Health Affairs, MoHP, Damietta 34711, Egypt.ORCID 0000-0001-7509-090X
Raed AlbiheyriBiological Science Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-9739-5496
Yousra A El-MaradnyProtein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria 21934, Egypt.ORCID 0000-0001-9501-8059
Ebtisam HassaninClinical Pathology Department, Faculty of Medicine, New Valley University, New Valley 72713, Egypt.
Noura ElsakaClinical Research Department, Directorate of Health Affairs, MoHP, Sharkia 71529, Egypt.
Ola FahmyEgyptian Drug Authority, Alexandria 21532, Egypt.
Ahmed AwdPhysical Therapy Department, Kafr El-Sheikh General Hospital, MoHP, Kafr El-Sheikh 33511, Egypt.
Heba AboeldahabClinical Research Department, Kom El-Shokafa Chest Hospital, MoHP, Alexandria 21572, Egypt.
Mai NayleClinical Research Department, Kafr El-Sheikh Chest Hospital, MoHP, Kafr El-Sheikh 33511, Egypt.
Magda AfifiGeneral Administration of Chest Diseases, MoHP, Cairo 11516, Egypt.
Marwa IbrahimClinical Research Department, Fakous Central Hospital, MoHP, Sharkia 71529, Egypt.
Raghda RafaatClinical Research Department, Fakous Central Hospital, MoHP, Sharkia 71529, Egypt.
Shahinda AlyClinical Research Department, Maamora Chest Hospital, MoHP, Alexandria 21923, Egypt.
Elrashdy M RedwanBiological Science Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0001-8246-0075
Kafrelsheikh University · EGKing Abdulaziz University · SACity of Scientific Research and Technological Applications · EGDamietta University · EGEgyptian Government · EGHealth Affairs · USNational Water Research Center · EGSouth Valley University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring a pandemic, healthcare workers are at high risk of contracting COVID-19. To protect these important individuals, it is highly recommended that they receive the COVID-19 vaccine. Our study focused on evaluating the safety and efficacy of Egypt's first approved vaccine, the Sinopharm vaccine (BBIBP-CorV), and comparing these findings with other vaccines.

methodsAn observational study was conducted in fifteen triage and isolation hospitals, from the 1st of March until the end of September 2021. The study included fully vaccinated and unvaccinated participants, and we measured vaccine effectiveness (using 1-aHR), the incidence rate of severely to critically ill hospitalized cases, COVID-19-related work absenteeism, and the safety of the vaccine as outcomes.

resultsOf the 1364 healthcare workers who were interviewed, 1228 agreed to participate. After taking the hazard ratio into account, the vaccine effectiveness was found to be 67% (95% CI, 80-43%) for symptomatic PCR-confirmed cases. The incidence rate ratio for hospitalization was 0.45 (95% CI, 0.15-1.31) in the vaccinated group compared to the unvaccinated group, and there was a significant reduction in absenteeism among the vaccinated group (

conclusionOur study found that the BBIBP-CorV vaccine was effective in protecting healthcare workers from COVID-19.

Indexed as

COVID-19healthcare workersSARS-CoV-2vaccinationvaccine effectivenessworkdays

Identifiers

PMID37242996
PMCPMC10224440
OpenAlexW4366991188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.