Evidence map›Paper›PMID 37242919›Full record

ReviewPolymers2023

Additive Manufacturing and Physicomechanical Characteristics of PEGDA Hydrogels: Recent Advances and Perspective for Tissue Engineering.

Mohammad Hakim Khalili, Rujing Zhang, Sandra Wilson, Saurav Goel, Susan A Impey, Adrianus Indrat Aria

Abstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Printable Piezoresistive Hybrid Hydrogels Based on 2D MoSAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Article
  6. Computational approaches in bioprinting processes.Nature reviews bioengineering · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Dynamic Hydrogels in Breast Tumor Models.Gels (Basel, Switzerland) · 2025
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad Hakim KhaliliSurface Engineering and Precision Centre, School of Aerospace, Transport and Manufacturing, Cranfield University, Bedford MK43 0AL, UK.ORCID 0000-0001-6185-6716
Rujing ZhangSophion Bioscience A/S, Baltorpvej 154, 2750 Copenhagen, Denmark.
Sandra WilsonSophion Bioscience A/S, Baltorpvej 154, 2750 Copenhagen, Denmark.
Saurav GoelSchool of Engineering, London South Bank University, 103 Borough Road, London SE1 0AA, UK.ORCID 0000-0002-8694-332X
Susan A ImpeySurface Engineering and Precision Centre, School of Aerospace, Transport and Manufacturing, Cranfield University, Bedford MK43 0AL, UK.
Adrianus Indrat AriaSurface Engineering and Precision Centre, School of Aerospace, Transport and Manufacturing, Cranfield University, Bedford MK43 0AL, UK.ORCID 0000-0002-6305-3906

Funding

British Council The Hubert Curien Partnership award 2022Royal Academy of Engineering Transforming the Partnership award (TSP1332)UK Research and Innovation EP/L016567/1UK Research and Innovation EP/S036180/1UK Research and Innovation EP/T001100/1UK Research and Innovation EP/T024607/1UK Research and Innovation EP/V029746/1
6 · The paper itself

Abstract

In this brief review, we discuss the recent advancements in using poly(ethylene glycol) diacrylate (PEGDA) hydrogels for tissue engineering applications. PEGDA hydrogels are highly attractive in biomedical and biotechnology fields due to their soft and hydrated properties that can replicate living tissues. These hydrogels can be manipulated using light, heat, and cross-linkers to achieve desirable functionalities. Unlike previous reviews that focused solely on material design and fabrication of bioactive hydrogels and their cell viability and interactions with the extracellular matrix (ECM), we compare the traditional bulk photo-crosslinking method with the latest three-dimensional (3D) printing of PEGDA hydrogels. We present detailed evidence combining the physical, chemical, bulk, and localized mechanical characteristics, including their composition, fabrication methods, experimental conditions, and reported mechanical properties of bulk and 3D printed PEGDA hydrogels. Furthermore, we highlight the current state of biomedical applications of 3D PEGDA hydrogels in tissue engineering and organ-on-chip devices over the last 20 years. Finally, we delve into the current obstacles and future possibilities in the field of engineering 3D layer-by-layer (LbL) PEGDA hydrogels for tissue engineering and organ-on-chip devices.

Indexed as

hydrogelspoly(ethylene glycol)diacrylateprintingthree-dimensionaltissue engineering

Identifiers

PMID37242919
PMCPMC10221499

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.