Evidence map›Paper›PMID 37242805›Full record

ArticlePharmaceutics2023

Differential Expression of

Wandong Zhang, Qing Yan Liu, Arsalan S Haqqani, Ziying Liu, Caroline Sodja, Sonia Leclerc, Ewa Baumann, Christie E Delaney, Eric Brunette, Danica B Stanimirovic

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Wandong ZhangHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.ORCID 0000-0001-6412-8124
Qing Yan LiuHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
Arsalan S HaqqaniHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
Ziying LiuScientific Data Mining/Digital Technology Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.ORCID 0000-0001-7821-6723
Caroline SodjaHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
Sonia LeclercHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
Ewa BaumannHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
Christie E DelaneyHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
Eric BrunetteHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
Danica B StanimirovicHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON K1A 0R6, Canada.
National Research Council Canada · CA

Funding

National Research Council of Canada A1-020800-01-01-01
6 · The paper itself

Abstract

backgroundATP-binding cassette (ABC) transporters comprise a superfamily of genes encoding membrane proteins with nucleotide-binding domains (NBD). These transporters, including drug efflux across the blood-brain barrier (BBB), carry a variety of substrates through plasma membranes against substrate gradients, fueled by hydrolyzing ATP. The expression patterns/enrichment of

methodsIn this study, the expression patterns of

resultsThe study demonstrated that

conclusionsThis study furthers the understanding of species similarities and differences in the expression patterns of

Indexed as

ABC transportersacross speciesbrain microvesselsgene expression patternsperipheral tissues and vesselsRNA-seqWesTM analysis

Identifiers

PMID37242805
PMCPMC10221359
OpenAlexW4378084486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.