Evidence map›Paper›PMID 37242795›Full record

ArticlePharmaceutics2023

Using Natural Deep Eutectic Systems as Alternative Media for Ocular Applications.

Célia Sarmento, Hugo Monteiro, Alexandre Paiva, Ana Rita C Duarte, Ana Rita Jesus

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Célia SarmentoLAQV-REQUIMTE, Chemistry Department, NOVA-School of Science and Technology, 2829-516 Caparica, Portugal.ORCID 0009-0004-4618-2361
Hugo MonteiroLAQV-REQUIMTE, Chemistry Department, NOVA-School of Science and Technology, 2829-516 Caparica, Portugal.
Alexandre PaivaLAQV-REQUIMTE, Chemistry Department, NOVA-School of Science and Technology, 2829-516 Caparica, Portugal.ORCID 0000-0003-0328-999X
Ana Rita C DuarteLAQV-REQUIMTE, Chemistry Department, NOVA-School of Science and Technology, 2829-516 Caparica, Portugal.
Ana Rita JesusLAQV-REQUIMTE, Chemistry Department, NOVA-School of Science and Technology, 2829-516 Caparica, Portugal.ORCID 0000-0002-0840-6289

Funding

European Research Council ERC-2016-CoG 725034
6 · The paper itself

Abstract

The major goal of this work was to study the potential of natural deep eutectic systems (NADES) as new media for ocular formulations. In formulating eye drops, it is important to increase the retention time of the drug on the surface of eye; hence, due to their high viscosity, NADES may be interesting candidates for formulation. Different systems composed of combinations of sugars, polyols, amino acids, and choline derivatives were prepared and then characterized in terms of rheological and physicochemical properties. Our results showed that 5-10% (

Indexed as

acetazolamidealternative solventsbiocompatibledrug deliverynatural deep eutectic systemsocular formulations

Identifiers

PMID37242795
PMCPMC10223266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.