Evidence map›Paper›PMID 37242778›Full record

ReviewPharmaceutics2023

The Role of Cyclodextrin in the Construction of Nanoplatforms: From Structure, Function and Application Perspectives.

Chengyuan Xing, Xiaoming Zheng, Tian Deng, Ling Zeng, Xin Liu, Xinjin Chi

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Cyclodextrins: Properties and Applications.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chengyuan XingInstitute of Sports Medicine and Health, Chengdu Sport University, Chengdu 610041, China.
Xiaoming ZhengThe Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.
Tian DengThe Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.
Ling ZengThe Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.
Xin LiuThe Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.
Xinjin ChiThe Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2020A1515011443Guangdong Basic and Applied Basic Research Foundation 2021A1515010669Shenzhen Fundamental Research Program JCYJ20210324115212033Shenzhen Fundamental Research Program JCYJ20220530144802005Shenzhen Science and Technology Program RCYX20200714114645131Sichuan Key Laboratory of Sports Medicine 2023-A004the Fundamental Research Funds for the Central Universities, Sun Yat-sen University 20ykpy17the National Natural Science Foundation of China 21704104
6 · The paper itself

Abstract

Cyclodextrins (CyDs) in nano drug delivery systems have received much attention in pursuit of good compatibility, negligible toxicity, and improved pharmacokinetics of drugs. Their unique internal cavity has widened the application of CyDs in drug delivery based on its advantages. Besides this, the polyhydroxy structure has further extended the functions of CyDs by inter- and intramolecular interactions and chemical modification. Furthermore, the versatile functions of the complex contribute to alteration of the physicochemical characteristics of the drugs, significant therapeutic promise, a stimulus-responsive switch, a self-assembly capability, and fiber formation. This review attempts to list recent interesting strategies regarding CyDs and discusses their roles in nanoplatforms, and may act as a guideline for developing novel nanoplatforms. Future perspectives on the construction of CyD-based nanoplatforms are also discussed at the end of this review, which may provide possible direction for the construction of more rational and cost-effective delivery vehicles.

Indexed as

applicationcyclodextrindrug deliveryhost-guest inclusioninteractions

Identifiers

PMID37242778
PMCPMC10221680

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.