Evidence map›Paper›PMID 37242762›Full record

ReviewPharmaceutics2023

Metal-Organic Framework-Based Nanomedicines for the Treatment of Intracellular Bacterial Infections.

Xiaoli Qi, Ningfei Shen, Aya Al Othman, Alexandre Mezentsev, Anastasia Permyakova, Zhihao Yu, Mathilde Lepoitevin, Christian Serre, Mikhail Durymanov

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Xiaoli QiMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Ningfei ShenMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Aya Al OthmanMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Alexandre MezentsevMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Anastasia PermyakovaFaculty of Chemistry, Lomonosov Moscow State University, 119234 Moscow, Russia.
Zhihao YuInstitute of Porous Materials from Paris (IMAP), Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, 75006 Paris, France.
Mathilde LepoitevinInstitute of Porous Materials from Paris (IMAP), Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, 75006 Paris, France.ORCID 0000-0003-0244-9939
Christian SerreInstitute of Porous Materials from Paris (IMAP), Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, 75006 Paris, France.
Mikhail DurymanovMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.ORCID 0000-0002-7894-7451
Moscow Institute of Physics and Technology · RUCentre National de la Recherche Scientifique · FRLomonosov Moscow State University · RU

Funding

China Scholarship Council 202008440250Ministry of Science and Higher Education of the Russian Federation № 075-15-2021-1363
6 · The paper itself

Abstract

Metal-organic frameworks (MOFs) are a highly versatile class of ordered porous materials, which hold great promise for different biomedical applications, including antibacterial therapy. In light of the antibacterial effects, these nanomaterials can be attractive for several reasons. First, MOFs exhibit a high loading capacity for numerous antibacterial drugs, including antibiotics, photosensitizers, and/or photothermal molecules. The inherent micro- or meso-porosity of MOF structures enables their use as nanocarriers for simultaneous encapsulation of multiple drugs resulting in a combined therapeutic effect. In addition to being encapsulated into an MOF's pores, antibacterial agents can sometimes be directly incorporated into an MOF skeleton as organic linkers. Next, MOFs contain coordinated metal ions in their structure. Incorporation of Fe

Indexed as

antibioticsbacteriaintracellular deliverymetal-organic frameworksnanomedicines

Identifiers

PMID37242762
PMCPMC10220673
OpenAlexW4377103879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.