Evidence map›Paper›PMID 37242756›Full record

ReviewPharmaceutics2023

Antibody-Loaded Nanoplatforms for Colorectal Cancer Diagnosis and Treatment: An Update.

Rania Djermane, Celia Nieto, Milena A Vega, Eva M Martín Del Valle

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rania DjermaneChemical Engineering Department, University of Salamanca, Plaza de los Caídos s/n, 37008 Salamanca, Spain.
Celia NietoChemical Engineering Department, University of Salamanca, Plaza de los Caídos s/n, 37008 Salamanca, Spain.ORCID 0000-0001-5484-5816
Milena A VegaChemical Engineering Department, University of Salamanca, Plaza de los Caídos s/n, 37008 Salamanca, Spain.ORCID 0000-0002-4296-0478
Eva M Martín Del ValleChemical Engineering Department, University of Salamanca, Plaza de los Caídos s/n, 37008 Salamanca, Spain.ORCID 0000-0003-3506-2546

Funding

Fundación Memoria Samuel Solorzano FS/5-2020The Spanish Ministry of Science and Innovation PDC2021-121393-I00University of Salamanca PIC2-2021-19
6 · The paper itself

Abstract

At present, colorectal cancer (CRC) is the second deadliest type of cancer, partly because a high percentage of cases are diagnosed at advanced stages when tumors have already metastasized. Thus, there is an urgent need to develop novel diagnostic systems that allow early detection as well as new therapeutic systems that are more specific than those currently available. In this context, nanotechnology plays a very important role in the development of targeted platforms. In recent decades, many types of nanomaterials with advantageous properties have been used for nano-oncology applications and have been loaded with different types of targeted agents, capable of recognizing tumor cells or biomarkers. Indeed, among the different types of targeted agents, the most widely used are monoclonal antibodies, as the administration of many of them is already approved by the main drug regulatory agencies for the treatment of several types of cancer, including CRC. In this way, this review comprehensively discusses the main drawbacks of the conventional screening technologies and treatment for CRC, and it presents recent advances in the application of antibody-loaded nanoplatforms for CRC detection, therapy or theranostics applications.

Indexed as

biosensorscolorectal cancercombination nanotherapydrug delivery systemsmonoclonal antibodiesnanoimagingnanomedicinetheranostics

Identifiers

PMID37242756
PMCPMC10224395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.