Evidence map›Paper›PMID 37242662›Full record

ArticlePharmaceutics2023

Preparation and In Vitro Characterization of Alkyl Polyglucoside-Based Microemulsion for Topical Administration of Curcumin.

Cristina Scomoroscenco, Mircea Teodorescu, Cristina Lavinia Nistor, Ioana Catalina Gifu, Cristian Petcu, Daniel Dumitru Banciu, Adela Banciu, Ludmila Otilia Cinteza

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cristina ScomoroscencoPolymer Department, National Institute for Research and Development in Chemistry and Petrochemistry-ICECHIM, 202 Spl. Independentei, 060021 Bucharest, Romania.
Mircea TeodorescuFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.ORCID 0000-0002-0333-911X
Cristina Lavinia NistorPolymer Department, National Institute for Research and Development in Chemistry and Petrochemistry-ICECHIM, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0002-9200-5807
Ioana Catalina GifuPolymer Department, National Institute for Research and Development in Chemistry and Petrochemistry-ICECHIM, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0002-2854-1998
Cristian PetcuPolymer Department, National Institute for Research and Development in Chemistry and Petrochemistry-ICECHIM, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0002-0624-4626
Daniel Dumitru BanciuDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Adela BanciuDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Ludmila Otilia CintezaPhysical Chemistry Department, University of Bucharest, 4-12 Blv. Regina Elisabeta, 030018 Bucharest, Romania.ORCID 0000-0002-3317-2787

Funding

Ministry of Research, Innovation and Digitization through Program 1 - Development of the na-tional research and development system, Subprogram 1.2 -Institutional performance - Projects to finance excellence in RDI Contract no. 15PFE/ 2021PN 23.06 Core Program - ChemNewDeal within the National Plan for Research, Development and Innovation 2022-2027, developed with the support of Ministry of Research, Innovation, and Digitization project no. PN 23.06.01.01
6 · The paper itself

Abstract

The skin is a complex and selective system from the perspective of permeability to substances from the external environment. Microemulsion systems have demonstrated a high performance in encapsulating, protecting and transporting active substances through the skin. Due to the low viscosity of microemulsion systems and the importance of a texture that is easy to apply in the cosmetic and pharmaceutical fields, gel microemulsions are increasingly gaining more interest. The aim of this study was to develop new microemulsion systems for topical use; to identify a suitable water-soluble polymer in order to obtain gel microemulsions; and to study the efficacy of the developed microemulsion and gel microemulsion systems in the delivery of a model active ingredient, namely curcumin, into the skin. A pseudo-ternary phase diagram was developed using AKYPO

Indexed as

curcumin deliverygel microemulsionmicroemulsionskin penetrationtopical formulationstransdermal delivery

Identifiers

PMID37242662
PMCPMC10220715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.