Evidence map›Paper›PMID 37242653›Full record

ReviewPharmaceutics2023

Systematic Review and Meta-Analysis of the Effect of Loop Diuretics on Antibiotic Pharmacokinetics.

David A Kerling, Sarah C Clarke, Jesse P DeLuca, Martin O Evans, Adrian T Kress, Robert J Nadeau, Daniel J Selig

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David A KerlingWalter Reed National Military Medical Center, Internal Medicine, Bethesda, MD 20889, USA.
Sarah C ClarkeWalter Reed National Military Medical Center, Internal Medicine, Bethesda, MD 20889, USA.ORCID 0000-0002-0016-6671
Jesse P DeLucaWalter Reed Army Institute of Research, Clinical Pharmacology Fellowship, Silver Spring, MD 20910, USA.
Martin O EvansWalter Reed Army Institute of Research, Clinical Pharmacology Fellowship, Silver Spring, MD 20910, USA.
Adrian T KressWalter Reed Army Institute of Research, Clinical Pharmacology Fellowship, Silver Spring, MD 20910, USA.
Robert J NadeauWalter Reed Army Institute of Research, Clinical Pharmacology Fellowship, Silver Spring, MD 20910, USA.
Daniel J SeligWalter Reed Army Institute of Research, Clinical Pharmacology Fellowship, Silver Spring, MD 20910, USA.ORCID 0000-0002-6107-5984
Walter Reed Army Institute of Research · USWalter Reed National Military Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loop diuretics and antibiotics are commonly co-prescribed across many clinical care settings. Loop diuretics may alter antibiotic pharmacokinetics (PK) via several potential drug interactions. A systematic review of the literature was performed to investigate the impact of loop diuretics on antibiotic PK. The primary outcome metric was the ratio of means (ROM) of antibiotic PK parameters such as area under the curve (AUC) and volume of distribution (V

Indexed as

antibioticsdrug interactionsloop diureticspharmacokinetics

Identifiers

PMID37242653
PMCPMC10224453
OpenAlexW4378515095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.