Evidence map›Paper›PMID 37242551›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Effect of the Composition of Leuzea and Cranberry Meal Extracts on Metabolic Processes in Norm and Pathology.

Daria Khalikova, Sergey An'kov, Nataliya Zhukova, Tatyana Tolstikova, Sergey Popov, Anastasia Saiko

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Daria KhalikovaVorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0002-3932-2491
Sergey An'kovVorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia.
Nataliya ZhukovaVorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia.
Tatyana TolstikovaVorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia.
Sergey PopovVorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia.
Anastasia SaikoVorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0001-7569-3268
Novosibirsk Institute of Organic Chemistry · RU

Funding

NIOCH SB RAS 1021051402785-4-1.4.1.
6 · The paper itself

Abstract

This study was conducted to evaluate the effects of long-term administration of a new herbal composition of leuzea and cranberry meal extracts at a dose of 70:500 mg/kg in healthy and pathological mice. After 4 weeks of daily composition administration to healthy CD-1 mice and C57BL/6 mice with diet-induced metabolic syndrome, oral glucose tolerance test (OGTT), serum biochemical examination and histology of internal organs were performed. Additionally, histological examination of white and brown adipose tissue was performed to evaluate the ability of the composition to prevent abdominal obesity in C57BL/6Ay (agouti yellow) mice. The results showed that the composition increased tissue sensitivity to glucose in healthy CD-1 mice; at the same time, it did not worsen the course of pathological processes in pathological mice. In both cases, the application of the developed composition was safe and contributed to the restoration of metabolic parameters.

Indexed as

adipocytescranberryecdysteneextractsleuzeametabolic syndromemiceursolic acid

Identifiers

PMID37242551
PMCPMC10221024
OpenAlexW4377092448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.