Evidence map›Paper›PMID 37242527›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Combination of Bacteriophages and Antibiotics for Prevention of Vascular Graft Infections-An In Vitro Study.

Stefan Ruemke, Evgenii Rubalskii, Christina Salmoukas, Kristina Hermes, Ruslan Natanov, Tim Kaufeld, Oleksandr Gryshkov, Vitalii Mutsenko, Maxim Rubalsky, Karin Burgwitz and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. [Phage therapy in Germany-Update 2025].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Stefan RuemkeDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Evgenii RubalskiiDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Christina SalmoukasDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Kristina HermesDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Ruslan NatanovDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-2219-3766
Tim KaufeldDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Oleksandr GryshkovLower Saxony Centre for Biomedical Engineering, Implant Research and Development, 30625 Hannover, Germany.ORCID 0000-0002-3116-8792
Vitalii MutsenkoLower Saxony Centre for Biomedical Engineering, Implant Research and Development, 30625 Hannover, Germany.
Maxim RubalskyDepartment of Microbiology and Virology, Astrakhan State Medical University, 414000 Astrakhan, Russia.
Karin BurgwitzDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Birgit GlasmacherLower Saxony Centre for Biomedical Engineering, Implant Research and Development, 30625 Hannover, Germany.
Axel HaverichDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Saad RustumDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Christian KuehnDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DELeibniz University Hannover · DEAstrakhan State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Implant-associated bacterial infections are usually hard to treat conservatively due to the resistance and tolerance of the pathogens to conventional antimicrobial therapy. Bacterial colonization of vascular grafts may lead to life-threatening conditions such as sepsis. The objective of this study is to evaluate whether conventional antibiotics and bacteriophages can reliably prevent the bacterial colonization of vascular grafts. (2) Methods: Gram-positive and Gram-negative bacterial infections were simulated on samples of woven PET gelatin-impregnated grafts using

Indexed as

antibioticsbacteriophagecoatingfibrin glueimplant-associated infectionpreventionvascular graft

Identifiers

PMID37242527
PMCPMC10223927
OpenAlexW4378514964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.