Evidence map›Paper›PMID 37242465›Full record

ReviewPharmaceuticals (Basel, Switzerland)2023

Photomodulation Approaches to Overcome Antimicrobial Resistance.

Sofia N Sarabando, Andreia Palmeira, Maria Emília Sousa, Maria Amparo F Faustino, Carlos J P Monteiro

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Antibacterial photoswitchable triazenic ciprofloxacins.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Synthesis of Tetra-The Journal of organic chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sofia N SarabandoLaboratory of Organic and Pharmaceutical Chemistry, Chemical Sciences Department, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Andreia PalmeiraLaboratory of Organic and Pharmaceutical Chemistry, Chemical Sciences Department, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-1391-2143
Maria Emília SousaLaboratory of Organic and Pharmaceutical Chemistry, Chemical Sciences Department, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-5397-4672
Maria Amparo F FaustinoLAQV-Requimte and Department of Chemistry, University of Aveiro, 3010-193 Aveiro, Portugal.ORCID 0000-0003-4423-3802
Carlos J P MonteiroLAQV-Requimte and Department of Chemistry, University of Aveiro, 3010-193 Aveiro, Portugal.ORCID 0000-0002-7773-3902
Universidade do Porto · PTUniversity of Aveiro · PT

Funding

Fundação para a Ciência e Tecnologia UIDB/04423/2020Fundação para a Ciência e Tecnologia UIDB/50006/2020Fundação para a Ciência e Tecnologia UIDP/04423/2020Fundação para a Ciência e Tecnologia UIDP/50006/2020
6 · The paper itself

Abstract

Photopharmacology is an approach that aims to be an alternative to classical chemotherapy. Herein, the different classes of photoswitches and photocleavage compounds and their biological applications are described. Proteolysis targeting chimeras (PROTACs) containing azobenzene moieties (PHOTACs) and photocleavable protecting groups (photocaged PROTACs) are also mentioned. Furthermore, porphyrins are referenced as successful photoactive compounds in a clinical context, such as in the photodynamic therapy of tumours as well as preventing antimicrobial resistance, namely in bacteria. Porphyrins combining photoswitches and photocleavage systems are highlighted, taking advantage of both photopharmacology and photodynamic action. Finally, porphyrins with antibacterial activity are described, taking advantage of the synergistic effect of photodynamic treatment and antibiotic therapy to overcome bacterial resistance.

Indexed as

antimicrobialsphotocagedphotopharmacologyphotoswitchporphyrin

Identifiers

PMID37242465
PMCPMC10221556
OpenAlexW4368375864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.