Evidence map›Paper›PMID 37242458›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Guanidines: Synthesis of Novel Histamine H

Marek Staszewski, Magdalena Iwan, Tobias Werner, Marek Bajda, Justyna Godyń, Gniewomir Latacz, Agnieszka Korga-Plewko, Joanna Kubik, Natalia Szałaj, Holger Stark and 3 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marek StaszewskiDepartment of Synthesis and Technology of Drugs, Medical University of Lodz, Muszyńskiego 1, 90-151 Łódź, Poland.ORCID 0000-0003-2783-522X
Magdalena IwanDepartment of Toxicology, Medical University of Lublin, Chodźki 8, 20-093 Lublin, Poland.ORCID 0000-0002-7834-0828
Tobias WernerInstitute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitaetsstr. 1, 40225 Duesseldorf, Germany.ORCID 0000-0002-7243-5826
Marek BajdaDepartment of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0001-6032-0354
Justyna GodyńDepartment of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0002-0295-2772
Gniewomir LataczDepartment of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0001-9247-2598
Agnieszka Korga-PlewkoIndependent Medical Biology Unit, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0000-0002-2027-9681
Joanna KubikIndependent Medical Biology Unit, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.ORCID 0000-0002-2766-3870
Natalia SzałajDepartment of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
Holger StarkInstitute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitaetsstr. 1, 40225 Duesseldorf, Germany.ORCID 0000-0003-3336-1710
Barbara MalawskaDepartment of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
Anna WięckowskaDepartment of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0003-2549-170X
Krzysztof WalczyńskiDepartment of Synthesis and Technology of Drugs, Medical University of Lodz, Muszyńskiego 1, 90-151 Łódź, Poland.ORCID 0000-0001-6223-3019

Funding

Medical Univeristy of Lodz 503/3-016-01/503-31-001-19-00Medical University of Lublin DS37Polish Smart Growth Operational Programme POIR 4.2 POIR.04.02.00-00-D023/20
6 · The paper itself

Abstract

This study examines the properties of novel guanidines, designed and synthesized as histamine H

Indexed as

antagonistbreast cancerguanidineshistamine H3 receptormulti-target directed ligand

Identifiers

PMID37242458
PMCPMC10223552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.