Evidence map›Paper›PMID 37242456›Full record

ReviewPharmaceuticals (Basel, Switzerland)2023

SUMOtherapeutics for Ischemic Stroke.

Paramesh Karandikar, Jakob V E Gerstl, Ari D Kappel, Sae-Yeon Won, Daniel Dubinski, Monica Emili Garcia-Segura, Florian A Gessler, Alfred Pokmeng See, Luca Peruzzotti-Jametti, Joshua D Bernstock

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Paramesh KarandikarT. H. Chan School of Medicine, University of Massachusetts, Worcester, MA 01655, USA.ORCID 0000-0002-3529-2037
Jakob V E GerstlDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0002-8100-0517
Ari D KappelDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
Sae-Yeon WonDepartment of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.
Daniel DubinskiDepartment of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.
Monica Emili Garcia-SeguraDepartment of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK.
Florian A GesslerDepartment of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.ORCID 0000-0002-3471-0575
Alfred Pokmeng SeeDepartment of Neurosurgery, Boston Children's Hospital, Boston, MA 02215, USA.
Luca Peruzzotti-JamettiDepartment of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-9396-5607
Joshua D BernstockDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
Brigham and Women's Hospital · USUniversity of Rostock · DEUniversity of Cambridge · GBBoston Children's Hospital · USUniversity of Massachusetts Chan Medical School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The small, ubiquitin-like modifier (SUMO) is a post-translational modifier with a profound influence on several key biological processes, including the mammalian stress response. Of particular interest are its neuroprotective effects, first recognized in the 13-lined ground squirrel (

Indexed as

experimental therapeuticsischemianeuroprotectionstrokeSUMOylation

Identifiers

PMID37242456
PMCPMC10221934
OpenAlexW4367627799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.