Evidence map›Paper›PMID 37242452›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Anti-Alopecia Activity of Coumarin Derivatives Isolated from

Syawal Abdurrahman, Ruslin Ruslin, Aliya Nur Hasanah, Mus Ifaya, Resmi Mustarichie

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Syawal AbdurrahmanDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia.
Ruslin RuslinDepartment of Medicinal Chemistry, Faculty of Pharmacy, Universitas Halu Oleo, Kendari 93231, Indonesia.
Aliya Nur HasanahDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia.ORCID 0000-0002-4085-7872
Mus IfayaDepartment of Pharmacy, Universitas Mandala Waluya, Kendari 93231, Indonesia.
Resmi MustarichieDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia.ORCID 0000-0001-6453-0236
Padjadjaran University · IDUniversitas Halu Oleo · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alopecia is a condition in which hair on the scalp or other areas of the body is lost or falls out excessively. Nutritional deficiency causes blood flow to the head to decrease causing the hormone testosterone to be changed by the enzyme 5-α-reductase to dihydrotestosterone, which inhibits the growth phase and accelerates the death phase. One of the methods developed to treat alopecia is through inhibition of the 5-α-reductase enzyme, which converts testosterone to its more potent metabolite, dihydrotestosterone (DHT). Ethnomedicinally,

Indexed as

ADME-Toxalopeciaenzyme 5-α-reductaseMerremia peltatamolecular dockingmolecular dynamicsscopoletinscopolin

Identifiers

PMID37242452
PMCPMC10222031
OpenAlexW4367311828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.