Evidence map›Paper›PMID 37242410›Full record

ArticlePathogens (Basel, Switzerland)2023

Mapping the Dynamics of Contemporary PRRSV-2 Evolution and Its Emergence and Spreading Hotspots in the U.S. Using Phylogeography.

Nakarin Pamornchainavakul, Igor A D Paploski, Dennis N Makau, Mariana Kikuti, Albert Rovira, Samantha Lycett, Cesar A Corzo, Kimberly VanderWaal

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nakarin PamornchainavakulDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0003-0378-0316
Igor A D PaploskiDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Dennis N MakauDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-1802-2545
Mariana KikutiDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Albert RoviraDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Samantha LycettRoslin Institute, University of Edinburgh, Edinburgh EH25 9RG, UK.ORCID 0000-0003-3159-596X
Cesar A CorzoDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-2749-3496
Kimberly VanderWaalDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-5764-6430
University of Minnesota · USRoslin Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/T004401/1
6 · The paper itself

Abstract

The repeated emergence of new genetic variants of PRRSV-2, the virus that causes porcine reproductive and respiratory syndrome (PRRS), reflects its rapid evolution and the failure of previous control efforts. Understanding spatiotemporal heterogeneity in variant emergence and spread is critical for future outbreak prevention. Here, we investigate how the pace of evolution varies across time and space, identify the origins of sub-lineage emergence, and map the patterns of the inter-regional spread of PRRSV-2 Lineage 1 (L1)-the current dominant lineage in the U.S. We performed comparative phylogeographic analyses on subsets of 19,395 viral ORF5 sequences collected across the U.S. and Canada between 1991 and 2021. The discrete trait analysis of multiple spatiotemporally stratified sampled sets (

Indexed as

disease emergencemolecular epidemiologyphylogeographyporcine reproductive and respiratory syndrome virussubsamplingvirus evolution

Identifiers

PMID37242410
PMCPMC10222675
OpenAlexW4377294677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.