Evidence map›Paper›PMID 37242310›Full record

ArticlePathogens (Basel, Switzerland)2023

Prevalence of Polyomaviruses and Herpesviruses in Moroccan Breast Cancer.

Amina Gihbid, Amal El Amrani, Fatima Zahra Mouh, Tarik Gheit, Mustapha Benhessou, Mariam Amrani, Sandrine McKay-Chopin, Selma Mohamed Brahim, Souha Sahraoui, Abdelouaheb Bennani and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Amina GihbidOncovirology Laboratory, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.ORCID 0000-0002-1958-0688
Amal El AmraniOncovirology Laboratory, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Fatima Zahra MouhOncogyma Research Unit, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat 10100, Morocco.
Tarik GheitInternational Agency for Research on Cancer, 69007 Lyon, France.ORCID 0000-0001-7088-337X
Mustapha BenhessouDepartment of Gynecological Obstetrics, Faculty of Medicine of Casablanca, Hospital University Center (CHU) Ibn Rochd Casablanca, Casablanca 20250, Morocco.
Mariam AmraniOncogyma Research Unit, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat 10100, Morocco.
Sandrine McKay-ChopinInternational Agency for Research on Cancer, 69007 Lyon, France.
Selma Mohamed BrahimOncovirology Laboratory, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Souha SahraouiMohammed VI Center for Cancer Treatment, Ibn Rochd University Hospital, Casablanca 20250, Morocco.
Abdelouaheb BennaniOncovirology Laboratory, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Mohammed El MzibriBiology and Medical Research Unit, National Centre of Energy, Nuclear Sciences and Technics, Rabat 10001, Morocco.ORCID 0000-0002-3148-1527
Meriem KhyattiOncovirology Laboratory, Institut Pasteur du Maroc, 1, Place Louis Pasteur, Casablanca 20360, Morocco.
Institut Pasteur du Maroc · MACentre Hospitalier Universitaire Ibn Rochd · MACentre international de recherche sur le cancer · FRMohammed V University · MANational Centre for Nuclear Energy, Science and Technology · MA

Funding

World Health Organization 001
6 · The paper itself

Abstract

Breast cancer (BC) is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for 24.5% of total new cancer cases and 15.5% of total cancer deaths. Similarly, BC is the most common cancer among Moroccan women, comprising a noteworthy percentage of 40% of all cancers in women. Globally, 15% of cancers are attributable to infections; among them, viruses play a significant role. The present study aimed to explore the presence of a wide range of viral DNA in samples recovered from 76 Moroccan patients with BC and 12 controls using Luminex technology. The explored viruses were as follows: 10 polyomaviruses (PyVs): BKV, KIV, JCV, MCV, WUV, TSV, HPyV6, HPyV7, HPyV9, and SV40; and 5 Herpesviruses (HHVs): CMV, EBV1, EBV2, HSV1, and HSV2. Our results revealed the presence of PyVs DNA in both control (16.7%) and BC tissues (18.4%). Nonetheless, HHV DNA was detected exclusively in BC tissues (23.7%), with a predominance of Epstein-Barr virus (EBV) (21%). In conclusion, our study highlights the presence of EBV in human BC tissues, which may play an important role in its development and/or progression. Further investigations are needed to confirm the presence/co-presence of these viruses in BC.

Indexed as

breast cancerherpesvirusesinfectionMoroccopolyomaviruses

Identifiers

PMID37242310
PMCPMC10224421
OpenAlexW4367054667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.