Evidence map›Paper›PMID 37242240›Full record

ArticleNutrients2023

Population Status of Vitamin B12 Values in the General Population and in Individuals with Type 2 Diabetes, in Southwestern Colombia.

Hernando Vargas-Uricoechea, Juan Patricio Nogueira, María V Pinzón-Fernández, Valentina Agredo-Delgado, Hernando David Vargas-Sierra

Registry-linked trialOpen access · goldFull text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06267053 (Investigation of the Relationship Between Vitamin B12, Folic Acid and 25 OH D Levels and Radiologic Stage in Knee Osteoarthritis), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06267053 completednot on this map

Investigation of the Relationship Between Vitamin B12, Folic Acid and 25 OH D Levels and Radiologic Stage in Knee Osteoarthritis

TypeobservationalSponsorBakirkoy Dr. Sadi Konuk Research and Training HospitalRan2023 to 2024Enrolled104ConditionsKnee OsteoarthritisArmsDirect digital radiography, 25-OH Vitamin D, Vitamin B12, Folic acid
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Vitamin BAnimals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Hernando Vargas-UricoecheaMetabolic Diseases Study Group, Department of Internal Medicine, Universidad del Cauca, Popayan 190003, Colombia.
Juan Patricio NogueiraCentro de Investigación en Endocrinología, Nutrición y Metabolismo (CIENM), Facultad de Ciencias de la Salud, Universidad Nacional de Formosa, Formosa 3600, Argentina.ORCID 0000-0002-8764-4700
María V Pinzón-FernándezHealth Research Group, Department of Internal Medicine, Universidad del Cauca, Popayan 190003, Colombia.
Valentina Agredo-DelgadoFellowship in Clinical Endocrinology and Metabolism, Universidad de Antioquia, Medellin 050010, Colombia.ORCID 0000-0002-5391-9665
Hernando David Vargas-SierraMetabolic Diseases Study Group, Department of Internal Medicine, Universidad del Cauca, Popayan 190003, Colombia.
University of Cauca · CONational University of Formosa · ARUniversidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin B12 (B12) is necessary for the proper functioning of the central and peripheral nervous systems. Although there is no exact definition for B12 levels, a value of 200 pg/mL is compatible with deficiency, 200-299 pg/mL is considered borderline, and 300 pg/mL is considered normal. In population studies, the prevalence of B12 deficiency ranges between 2.9% and 35%. Furthermore, many medications, such as metformin [for type 2 diabetes mellitus (T2DM)], can cause B12 deficiency. The objectives of this study were to determine the population status of B12 in southwestern Colombia (and the status of B12 in subjects with T2DM). In the total population (participants with and without T2DM), the prevalence of B12 deficiency was 17.8%; that of borderline was 19.3%; and that of normal levels was 62.9%. The prevalence of deficiency increased with age and was significantly higher in those aged ≥60 years (

Indexed as

Diabetes Mellitus, Type 2MetforminVitamin B 12 DeficiencyColombiaHumansHypoglycemic AgentsMiddle AgedVitamin B 12Hypoglycemic AgentsMetforminVitamin B 12B12deficiencydiabetesmetforminvitamin

Identifiers

PMID37242240
PMCPMC10221874
OpenAlexW4377108073

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.