Evidence map›Paper›PMID 37242184›Full record

SynthesisNutrients2023

Knowledge and Beliefs about Herb/Supplement Consumption and Herb/Supplement-Drug Interactions among the General Population, including Healthcare Professionals and Pharmacists: A Systematic Review and Guidelines for a Smart Decision System.

Artemisa R Dores, Miguel Peixoto, Maria Castro, Catarina Sá, Irene P Carvalho, Andreia Martins, Eva Maia, Isabel Praça, António Marques

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  13. Review
  14. Review
  15. Dietary Supplements for Weight Loss and Drug Interactions.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
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  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Artemisa R DoresLaboratório de Reabilitação Psicossocial, Centro de Investigação em Reabilitação (CIR), Escola Superior de Saúde, Instituto Politécnico do Porto (ESS-IPP), 4200-072 Porto, Portugal.ORCID 0000-0003-4595-9816
Miguel PeixotoLaboratório de Reabilitação Psicossocial, Centro de Investigação em Reabilitação (CIR), Escola Superior de Saúde, Instituto Politécnico do Porto (ESS-IPP), 4200-072 Porto, Portugal.
Maria CastroLaboratório de Reabilitação Psicossocial, Centro de Investigação em Reabilitação (CIR), Escola Superior de Saúde, Instituto Politécnico do Porto (ESS-IPP), 4200-072 Porto, Portugal.ORCID 0000-0003-3600-7397
Catarina SáLaboratório de Reabilitação Psicossocial, Centro de Investigação em Reabilitação (CIR), Escola Superior de Saúde, Instituto Politécnico do Porto (ESS-IPP), 4200-072 Porto, Portugal.ORCID 0000-0002-5144-2269
Irene P CarvalhoClinical Neurosciences and Mental Health Department, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0001-7981-4442
Andreia MartinsResearch Group on Intelligent Engineering and Computing for Advanced Innovation and Development (GECAD), School of Engineering, Polytechnic of Porto (ISEP/IPP), 4249-015 Porto, Portugal.ORCID 0000-0001-8017-7460
Eva MaiaResearch Group on Intelligent Engineering and Computing for Advanced Innovation and Development (GECAD), School of Engineering, Polytechnic of Porto (ISEP/IPP), 4249-015 Porto, Portugal.ORCID 0000-0002-8075-531X
Isabel PraçaResearch Group on Intelligent Engineering and Computing for Advanced Innovation and Development (GECAD), School of Engineering, Polytechnic of Porto (ISEP/IPP), 4249-015 Porto, Portugal.ORCID 0000-0002-2519-9859
António MarquesLaboratório de Reabilitação Psicossocial, Centro de Investigação em Reabilitação (CIR), Escola Superior de Saúde, Instituto Politécnico do Porto (ESS-IPP), 4200-072 Porto, Portugal.ORCID 0000-0002-8656-5023
Polytechnic Institute of Porto · PTUniversidade do Porto · PT

Funding

Project ForPharmacy - Future pharmacy as a plug-and-play ecosystem (PO-CI-01-0247-FEDER-070053/ LISBOA-01-0247-FEDER-070053), funded by the European Regional Development Fund (ERDF), under the Competitiveness and Internationalisation Operational Pro-gramm POCI-01-0247-FEDER-070053/ LISBOA-01-0247-FEDER-070053This work was supported by Fundação para a Ciência e Tecnologia (FCT) through R&D Units funding (UIDB/05210/2020) and under the project UIDB/05422/2020. UIDB/05422/2020
6 · The paper itself

Abstract

The increased consumption of a variety of herbs/supplements has been raising serious health concerns. Owing to an inadequate understanding of herb/supplement-drug interactions, the simultaneous consumption of these products may result in deleterious effects and, in extreme cases, even fatal outcomes. This systematic review is aimed at understanding the knowledge and beliefs about the consumption of herbs/supplements and herb/drug-supplement interactions (HDIs). The study follows the PRISMA guidelines. Four online databases (Web of Science; PubMed; Cochrane; and EBSCOhost) were searched, and a total of 44 studies were included, encompassing 16,929 participants. Herb and supplement consumption is explained mostly by the reported benefits across multiple conditions and ease of use. Regarding HDIs, most people take both herbs/supplements and prescription drugs simultaneously. Only a small percentage of participants have knowledge about their interaction effects, and many reported adverse interactions or side effects. Nevertheless, the main reason for stopping the prescribed drug intake is the perceived lack of its effect, and not due to interactions. Therefore, it is important to increase the knowledge about supplement use so that further strategies can be elaborated to better detect or be alert for whenever a potentially dangerous reaction and/or interaction may occur. This paper raises awareness regarding the need for developing a decision support system and ends with some considerations about the development of a technological solution capable of detecting HDIs and, thereby, aiding in the improvement of pharmacy services.

Indexed as

Drug-Related Side Effects and Adverse ReactionsPharmacistsDelivery of Health CareDietary SupplementsHerb-Drug InteractionsHumansbeliefsherb/supplement–drug interaction (HDI)knowledgeperceptions: attitudespharmacy

Identifiers

PMID37242184
PMCPMC10220613
OpenAlexW4378516048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.