Evidence map›Paper›PMID 37242151›Full record

ArticleNutrients2023

GPR-160 Receptor Signaling in the Dorsal Vagal Complex of Male Rats Modulates Meal Microstructure and CART-Mediated Hypophagia.

Marcos J Sanchez-Navarro, Tito Borner, Benjamin C Reiner, Richard C Crist, Willis K Samson, Gina L C Yosten, Lauren Stein, Matthew R Hayes

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. American journal of physiology. Endocrinology and metabolism · 2026
    Article
  5. Article
  6. Article
  7. Convergent state-control of endogenous opioid analgesia.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marcos J Sanchez-NavarroDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-3099-788X
Tito BornerDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Benjamin C ReinerDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-7796-587X
Richard C CristDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Willis K SamsonDepartment of Pharmacology and Physiology, Saint Louis University School of Medicine, 1402 S. Grand Boulevard, Saint Louis, MO 63104, USA.
Gina L C YostenDepartment of Pharmacology and Physiology, Saint Louis University School of Medicine, 1402 S. Grand Boulevard, Saint Louis, MO 63104, USA.
Lauren SteinDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Matthew R HayesDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-9782-6551
University of Pennsylvania · USSaint Louis University · US

Funding

Astrocytes mediate GLP-1 effects on energy balanceR01DK115762 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI HAYES, MATTHEW R · 2018 to 2022
$2.8M
Integrative Physiology of Obesity: Role of GPR160R01DK118340 · NIDDK · SAINT LOUIS UNIVERSITY · PI YOSTEN, GINA L.C. · 2018 to 2022
$2.3M
Astrocytes mediate GLP-1 effects on energy balanceR56DK115762 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI HAYES, MATTHEW R · 2017 to 2017
$211k
NIDDK NIH HHS DK115762NIDDK NIH HHS DK118340NIDDK NIH HHS R01 DK115762NIDDK NIH HHS R01 DK118340NIDDK NIH HHS R56 DK115762
6 · The paper itself

Abstract

The g-protein coupled receptor GPR-160, recently identified as a putative receptor for the cocaine and amphetamine-regulated transcript (CART) peptide, shows abundant expression in the energy-balance control nuclei, including the dorsal vagal complex (DVC). However, its physiological role in the control of food intake has yet to be fully explored. Here, we performed a virally mediated, targeted knockdown (KD) of

Indexed as

Solitary NucleusVagus NerveAnimalsMaleNeuronsRatsRats, Sprague-DawleyCARTdorsal vagal complexfeedingGPR-160microglia

Identifiers

PMID37242151
PMCPMC10221706
OpenAlexW4376137573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.