Evidence map›Paper›PMID 37242005›Full record

ReviewNanomaterials (Basel, Switzerland)2023

Biodegradable Microrobots and Their Biomedical Applications: A Review.

Jinxin Li, Jiangfan Yu

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  3. Article
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  9. Review
  10. Article
  11. Recent Advances in Electrospinning Techniques for Precise Medicine.Cyborg and bionic systems (Washington, D.C.) · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Emerging Applications ofBioengineering (Basel, Switzerland) · 2023
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jinxin LiSchool of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China.
Jiangfan YuSchool of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China.

Funding

CUHK-Shenzhen UDF01001929Guangdong Basic and Applied Basic Research Foundation 2023A1515012973National Natural Science Foundation of China 62103347Shenzhen Science and Technology Program RCBS20210609103155061
6 · The paper itself

Abstract

During recent years, microrobots have drawn extensive attention owing to their good controllability and great potential in biomedicine. Powered by external physical fields or chemical reactions, these untethered microdevices are promising candidates for in vivo complex tasks, such as targeted delivery, imaging and sensing, tissue engineering, hyperthermia, and assisted fertilization, among others. However, in clinical use, the biodegradability of microrobots is significant for avoiding toxic residue in the human body. The selection of biodegradable materials and the corresponding in vivo environment needed for degradation are increasingly receiving attention in this regard. This review aims at analyzing different types of biodegradable microrobots by critically discussing their advantages and limitations. The chemical degradation mechanisms behind biodegradable microrobots and their typical applications are also thoroughly investigated. Furthermore, we examine their feasibility and deal with the in vivo suitability of different biodegradable microrobots in terms of their degradation mechanisms; pathological environments; and corresponding biomedical applications, especially targeted delivery. Ultimately, we highlight the prevailing obstacles and perspective solutions, ranging from their manufacturing methods, control of movement, and degradation rate to insufficient and limited in vivo tests, that could be of benefit to forthcoming clinical applications.

Indexed as

biodegradablebiomedicinemicro/nanomotorsmicro/nanorobotstargeted delivery

Identifiers

PMID37242005
PMCPMC10221485

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.