Critical Evaluation of Two Qualitative Analytical Approaches for Multiclass Determination of Veterinary Drugs in Bovine Muscle Using UHPLC-Q-Orbitrap: The Wind of Change in Brazilian Monitoring.

Ramon Alves de Oliveira Paula, Carina de Souza Gondim, Eduardo Morgado Schmidt, Maria Helena Glicério Marcelina Diniz, Mary Ane Gonçalves Lana, Leandro Soares de Oliveira

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Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

6 authors.

Ramon Alves de Oliveira PaulaPostgraduate Program in Food Science, Department of Food Science (ALM), Faculty of Pharmacy (FAFAR), Federal University of Minas Gerais (UFMG), Campus da UFMG, Antônio Carlos Avenue 6627, Belo Horizonte 31270-010, Brazil.ORCID 0000-0002-4562-0970

Carina de Souza GondimPostgraduate Program in Food Science, Department of Food Science (ALM), Faculty of Pharmacy (FAFAR), Federal University of Minas Gerais (UFMG), Campus da UFMG, Antônio Carlos Avenue 6627, Belo Horizonte 31270-010, Brazil.

Eduardo Morgado SchmidtNova Analítica Importações e Exportações LTDA, Assungui Street, 432, Vila Gumercindo, São Paulo 04131-000, Brazil.

Maria Helena Glicério Marcelina DinizFood of the Agricultural Defense Federal Laboratory of Minas Gerais, Ministry of Agriculture and Livestock, Rômulo Joviano Avenue, s/nº, Centro, Pedro Leopoldo 33600-000, Brazil.

Mary Ane Gonçalves LanaFood of the Agricultural Defense Federal Laboratory of Minas Gerais, Ministry of Agriculture and Livestock, Rômulo Joviano Avenue, s/nº, Centro, Pedro Leopoldo 33600-000, Brazil.

Leandro Soares de OliveiraPostgraduate Program in Food Science, Department of Food Science (ALM), Faculty of Pharmacy (FAFAR), Federal University of Minas Gerais (UFMG), Campus da UFMG, Antônio Carlos Avenue 6627, Belo Horizonte 31270-010, Brazil.ORCID 0000-0001-6977-7625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food safety is recognized as a main requirement for consumers, food industries, and official laboratories. Here, we present the optimization and screening qualitative validation of two multianalyte methods in bovine muscle tissues by ultra-high-performance liquid chromatography coupled to high-resolution mass spectrometry with an Orbitrap-type analyzer, operated with a heated ionization source in positive and negative mode. This aims for not only the simultaneous detection of veterinary drugs regulated in Brazil but also the prospection of antimicrobials not yet monitored. Two different sample preparation procedures were applied: method A-generic solid-liquid extraction with 0.1% formic acid (

Indexed as

Veterinary DrugsAnimalsBrazilCattleChromatography, High Pressure LiquidLimit of DetectionMusclesVeterinary Drugsdrug metabolitesfood analysisfood analytical chemistryfood of animal originfood safetyhigh-resolution mass spectrometrymeat matricesmulti-class multi-residue analysissample treatmenttargeted-screening method

Identifiers

PMID37241891

DOI10.3390/molecules28104150

PMCPMC10222520

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.