Evidence map›Paper›PMID 37241805›Full record

ArticleMolecules (Basel, Switzerland)2023

UPLC-QE-Orbitrap-Based Cell Metabolomics and Network Pharmacology to Reveal the Mechanism of N-Benzylhexadecanamide Isolated from Maca (

Kai-Yue Zhang, Chun-Nan Li, Nan-Xi Zhang, Xiao-Chen Gao, Jia-Ming Shen, Duan-Duan Cheng, Yue-Long Wang, Hui Zhang, Jing-Wei Lv, Jia-Ming Sun

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Effects of Maca (Nutrients · 2024
    Pooled it
  2. Global Research Status of Maca (Drug design, development and therapy · 2025
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kai-Yue ZhangJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID 0009-0001-2458-0789
Chun-Nan LiJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID 0000-0002-4212-0428
Nan-Xi ZhangJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID 0000-0003-1788-6402
Xiao-Chen GaoJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Jia-Ming ShenJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Duan-Duan ChengJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Yue-Long WangJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Hui ZhangJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Jing-Wei LvJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Jia-Ming SunJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID 0000-0002-0043-9449
Changchun University of Chinese Medicine · CN

Funding

Jilin Province Development and Reform Commission 2022011Jilin Province Science and Technology Department 20200404081YYNational Natural Science Foundation of China 31570347
6 · The paper itself

Abstract

Testicular dysfunction (TDF) is characterized by testosterone deficiency and is caused by oxidative stress injury in Leydig cells. A natural fatty amide named N-benzylhexadecanamide (NBH), derived from cruciferous maca, has been shown to promote testosterone production. Our study aims to reveal the anti-TDF effect of NBH and explore its potential mechanism in vitro. This study examined the effects of H

Indexed as

LepidiumTandem Mass SpectrometryAnimalsHydrogen PeroxideMaleMetabolomicsMiceNetwork PharmacologyPolyunsaturated AlkamidesTestosteroneHydrogen PeroxideN-benzylhexadecanamidePolyunsaturated AlkamidesTestosteronemechanismsmetabolomicsN-benzylhexadecanamidenetwork pharmacologytesticular dysfunction

Identifiers

PMID37241805
PMCPMC10222419
OpenAlexW4378516537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.