Evidence map›Paper›PMID 37241762›Full record

ArticleMolecules (Basel, Switzerland)2023

A New Self-Healing Degradable Copolymer Based on Polylactide and Poly(p-dioxanone).

Laifa Tong, Mi Zhou, Yulong Chen, Kai Lu, Zhaohua Zhang, Yuesong Mu, Zejian He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Catechol redox maintenance in mussel adhesion.Nature reviews. Chemistry · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laifa TongMaterial Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.
Mi ZhouMaterial Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.ORCID 0000-0001-8588-878X
Yulong ChenMaterial Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.
Kai LuMaterial Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.
Zhaohua ZhangMaterial Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.
Yuesong MuMaterial Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.
Zejian HeMaterial Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, the copolymerization of poly (p-dioxanone) (PPDO) and polylactide (PLA) was carried out via a Diels-Alder reaction to obtain a new biodegradable copolymer with self-healing abilities. By altering the molecular weights of PPDO and PLA precursors, a series of copolymers (DA2300, DA3200, DA4700 and DA5500) with various chain segment lengths were created. After verifying the structure and molecular weight by 1H NMR, FT-IR and GPC, the crystallization behavior, self-healing properties and degradation properties of the copolymers were evaluated by DSC, POM, XRD, rheological measurements and enzymatic degradation. The results show that copolymerization based on the DA reaction effectively avoids the phase separation of PPDO and PLA. Among the products, DA4700 showed a better crystallization performance than PLA, and the half-crystallization time was 2.8 min. Compared to PPDO, the heat resistance of the DA copolymers was improved and the Tm increased from 93 °C to 103 °C. Significantly, the rheological data also confirmed that the copolymer was self-healing and showed obvious self-repairing properties after simple tempering. In addition, an enzyme degradation experiment showed that the DA copolymer can be degraded by a certain amount, with the degradation rate lying between those of PPDO and PLA.

Indexed as

crystallization behaviorDiels–Alder reactionpolylactidepoly(p-dioxanone)self-healing

Identifiers

PMID37241762
PMCPMC10223814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.