Evidence map›Paper›PMID 37241738›Full record

ArticleMolecules (Basel, Switzerland)2023

Amelioration of Obesity-Related Disorders in High-Fat Diet-Fed Mice following Fecal Microbiota Transplantation from Inulin-Dosed Mice.

Yinli Huang, Na Ying, Qihui Zhao, Junli Chen, Sin-Yeang Teow, Wei Dong, Minjie Lin, Lingling Jiang, Hong Zheng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  12. Frontiers in pharmacology · 2024
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yinli HuangDepartment of Endocrinology, Pingyang Affiliated Hospital of Wenzhou Medical University, Wenzhou 325400, China.
Na YingSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Qihui ZhaoSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Junli ChenSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Sin-Yeang TeowCollege of Science and Technology, Wenzhou-Kean University, Wenzhou 325060, China.ORCID 0000-0002-3824-0224
Wei DongDepartment of Endocrinology, Pingyang Affiliated Hospital of Wenzhou Medical University, Wenzhou 325400, China.
Minjie LinDepartment of Endocrinology, Pingyang Affiliated Hospital of Wenzhou Medical University, Wenzhou 325400, China.
Lingling JiangCollege of Science and Technology, Wenzhou-Kean University, Wenzhou 325060, China.
Hong ZhengDepartment of Endocrinology, Pingyang Affiliated Hospital of Wenzhou Medical University, Wenzhou 325400, China.ORCID 0000-0002-3401-721X
Wenzhou Medical University · CNWenzhou-Kean University · CN

Funding

Medical and Health Science and Technology Project of Zhejiang Province 2022KY1215
6 · The paper itself

Abstract

The role of inulin in alleviating obesity-related disorders has been documented; yet, its underlying mechanisms still need to be further investigated. This study attempted to elucidate the causative link between the gut microbiota and the beneficial effect of inulin on obesity-related disorders via transferring the fecal microbiota from inulin-dosed mice to high-fat diet (HFD)-induced obese recipient mice. The results show that inulin supplementation can decrease body weight, fat accumulation, and systemic inflammation and can also enhance glucose metabolism in HFD-induced obese mice. Treatment with inulin reshaped the structure and composition of the gut microbiota in HFD-induced obese mice, as characterized by increases in the relative abundances of

Indexed as

Diet, High-FatInulinAnimalsFecal Microbiota TransplantationMiceMice, Inbred C57BLMice, ObeseObesityInulingut microbiotainflammationinulinliverobesity

Identifiers

PMID37241738
PMCPMC10221449
OpenAlexW4378516137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.