ReviewMedicina (Kaunas, Lithuania)2023
Challenges in Local Allergic Rhinitis Diagnosis, Management, and Research: Current Concepts and Future Perspectives.
Review in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Timothy Grass Pollen-Specific Immunoglobulin E in Nasal Secretions During Natural Allergen Exposure and After a Nasal Provocation Test in Patients with Suspected Local Allergic Rhinitis.Advances in respiratory medicine · 2026Article
- Using Local sIgE Threshold to Refine the Diagnosis of Local Allergic Rhinitis.International forum of allergy & rhinology · 2026Article
- MicroRNAs as current diagnostic biomarkers and potential therapeutic targets in allergic and non-allergic rhinitis - A functional characterization.Current allergy and asthma reports · 2026Review
- Molecular Biomarkers in IgE Immunoassays Used for Grass Pollen Allergy Diagnosis in European Clinical Settings.International journal of molecular sciences · 2026Review
- P2 Receptors as Therapeutic Targets in Allergic Rhinitis: Insights From the Use of Natural Products and Preclinical Studies.Journal of immunology research · 2026Review
- Do Skin Prick Tests Predict Nasal Provocation Test Outcomes in Allergic Rhinitis Patients?International forum of allergy & rhinology · 2025Article
- Aeroallergen IgE-Reactivity Patterns and Respiratory Allergy in Children and Adults: A Retrospective Study in 1711 Patients from the Central Poland Urban Area.Medicina (Kaunas, Lithuania) · 2025Article
- The Association of Nasal and Blood Eosinophils with Serum IgE Level in Allergic Rhinitis and Asthma: A Case-Control Study.Health science reports · 2024Article
- Diagnostic Workup in IgE-Mediated Allergy to Asteraceae Weed Pollen and Herbal Medicine Products in Europe.Medicina (Kaunas, Lithuania) · 2024Review
- [Immunoglobulin E in nasal secretions].HNO · 2024Review
- Local Allergic Rhinitis-A Challenge for Allergology and Otorhinolaryngology Cooperation (Scoping Review).Life (Basel, Switzerland) · 2024Review
- The Impact of Cytokines on Health-Related Quality of Life in Adolescents with Allergic Rhinitis.Biomedicines · 2024Article
- Epidemiology of Childhood Asthma in the UK.Journal of asthma and allergy · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Local allergic rhinitis (LAR) is diagnosed based on the presence of clinical symptoms such as rhinorrhea, sneezing, and nasal itching using negative skin prick testing and serum IgE assessment. Several novel studies have shown that it is possible to use the assessment of nasal sIgE (specific immunoglobulin E) secretion as an additional diagnostic criterion for local allergic rhinitis. Additionally, allergen immunotherapy is a promising-albeit still not fully assessed and evaluated-future method of managing patients with LAR. In this review, the historical background, epidemiology, and main pathophysiological mechanisms of LAR shall be presented. Additionally, we address the current state of knowledge based on selected articles regarding the assessment of the local mucosal IgE presence in response to exposure to such allergens as mites, pollen, molds, and others. The impact of LAR on quality of life as well as the possible options of management (including allergen immunotherapy (AIT), which showed promising results) will then be presented.
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