Evidence map›Paper›PMID 37240919›Full record

ReviewJournal of personalized medicine2023

Review of Endometrial Receptivity Array: A Personalized Approach to Embryo Transfer and Its Clinical Applications.

Sarah C Rubin, Mawerdi Abdulkadir, Joshua Lewis, Aleksandr Harutyunyan, Rahim Hirani, Cara L Grimes

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sarah C RubinSchool of Medicine, New York Medical College, 40 Sunshine Cottage Road, Valhalla, NY 10595, USA.ORCID 0009-0008-7609-2307
Mawerdi AbdulkadirSchool of Medicine, New York Medical College, 40 Sunshine Cottage Road, Valhalla, NY 10595, USA.
Joshua LewisSchool of Medicine, New York Medical College, 40 Sunshine Cottage Road, Valhalla, NY 10595, USA.
Aleksandr HarutyunyanSchool of Medicine, New York Medical College, 40 Sunshine Cottage Road, Valhalla, NY 10595, USA.
Rahim HiraniSchool of Medicine, New York Medical College, 40 Sunshine Cottage Road, Valhalla, NY 10595, USA.ORCID 0000-0002-9304-9916
Cara L GrimesSchool of Medicine, New York Medical College, 40 Sunshine Cottage Road, Valhalla, NY 10595, USA.
New York Medical College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Successful outcomes of in vitro fertilization (IVF) rely on both the formation of a chromosomally normal embryo and its implantation in a receptive endometrium. Pre-implantation genetic testing for aneuploidy (PGT-A) has been widely accepted as a tool to assess the viability of an embryo. In 2011, the endometrial receptivity array (ERA) was first published as a tool to determine when the endometrium is most receptive to an embryo, commonly referred to as the "window of implantation" (WOI). The ERA uses molecular arrays to assess proliferation and differentiation in the endometrium and screens for inflammatory markers. Unlike PGT-A, there has been dissent within the field concerning the efficacy of the ERA. Many studies that contest the success of the ERA found that it did not improve pregnancy outcomes in patients with an already-good prognosis. Alternatively, studies that utilized the ERA in patients with repeated implantation failure (RIF) and transfer of known euploid embryos demonstrated improved outcomes. This review aims to describe the ERA as a novel technique, review the various settings that the ERA may be used in, such as natural frozen embryo transfer (nFET) and hormone replacement therapy frozen embryo transfer (HRT-FET), and provide a summary of the recent clinical data for embryo transfers in patients with RIF utilizing the ERA.

Indexed as

endometrial receptivity arrayfrozen embryo transferhormone replacement therapyimplantation failurein vitro fertilizationpre-implantation testing

Identifiers

PMID37240919
PMCPMC10219399
OpenAlexW4367298745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.