Evidence map›Paper›PMID 37240887›Full record

ArticleJournal of personalized medicine2023

Development and Validation of Artificial-Intelligence-Based Radiomics Model Using Computed Tomography Features for Preoperative Risk Stratification of Gastrointestinal Stromal Tumors.

Marco Rengo, Alessandro Onori, Damiano Caruso, Davide Bellini, Francesco Carbonetti, Domenico De Santis, Simone Vicini, Marta Zerunian, Elsa Iannicelli, Iacopo Carbone and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marco RengoDepartment of Medical-Surgical Sciences and Biotechnologies, Academic Diagnostic Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy.ORCID 0000-0001-9087-5692
Alessandro OnoriDepartment of Radiological, Oncological and Pathological Sciences, Academic Diagnostic Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy.
Damiano CarusoDepartment of Surgical and Medical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, University of Rome Sapienza, Via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0001-9285-4764
Davide BelliniDepartment of Medical-Surgical Sciences and Biotechnologies, Academic Diagnostic Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy.
Francesco CarbonettiRadiology Unit, Sant'Eugenio Hospital, Piazzale dell'Umanesimo 10, 00144 Rome, Italy.
Domenico De SantisDepartment of Surgical and Medical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, University of Rome Sapienza, Via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0002-1197-456X
Simone ViciniDepartment of Medical-Surgical Sciences and Biotechnologies, Academic Diagnostic Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy.
Marta ZerunianDepartment of Surgical and Medical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, University of Rome Sapienza, Via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0003-4635-7999
Elsa IannicelliDepartment of Surgical and Medical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, University of Rome Sapienza, Via di Grottarossa 1035, 00189 Rome, Italy.
Iacopo CarboneDepartment of Radiological, Oncological and Pathological Sciences, Academic Diagnostic Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy.
Andrea LaghiDepartment of Surgical and Medical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, University of Rome Sapienza, Via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0002-3091-7819
Sapienza University of Rome · ITSt. Eugenio Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundpreoperative risk assessment of gastrointestinal stromal tumors (GISTS) is required for optimal and personalized treatment planning. Radiomics features are promising tools to predict risk assessment. The purpose of this study is to develop and validate an artificial intelligence classification algorithm, based on CT features, to define GIST's prognosis as determined by the Miettinen classification.

methodspatients with histological diagnosis of GIST and CT studies were retrospectively enrolled. Eight morphologic and 30 texture CT features were extracted from each tumor and combined to obtain three models (morphologic, texture and combined). Data were analyzed using a machine learning classification (WEKA). For each classification process, sensitivity, specificity, accuracy and area under the curve were evaluated. Inter- and intra-reader agreement were also calculated.

results52 patients were evaluated. In the validation population, highest performances were obtained by the combined model (SE 85.7%, SP 90.9%, ACC 88.8%, and AUC 0.954) followed by the morphologic (SE 66.6%, SP 81.8%, ACC 76.4%, and AUC 0.742) and texture (SE 50%, SP 72.7%, ACC 64.7%, and AUC 0.613) models. Reproducibility was high of all manual evaluations.

conclusionsthe AI-based radiomics model using a CT feature demonstrates good predictive performance for preoperative risk stratification of GISTs.

Indexed as

artificial intelligencecomputed tomographygastrointestinal stromal tumormachine learningprognosticradiomicsrisk assessment

Identifiers

PMID37240887
PMCPMC10219425
OpenAlexW4366988166

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.