Evidence map›Paper›PMID 37240876›Full record

ArticleJournal of personalized medicine2023

Endotypes of Nasal Polyps in Children: A Multidisciplinary Approach.

Emanuela Sitzia, Sara Santarsiero, Giulia Marini, Fabio Majo, Marcello De Vincentiis, Giovanni Cristalli, Maria Cristina Artesani, Alessandro Giovanni Fiocchi

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Unanswered questions on the use of biologics in pediatric asthma.The World Allergy Organization journal · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Emanuela SitziaDepartment of Otorhinolaryngology, Children's Hospital "Ospedale Pediatrico Bambino Gesù-IRCCS", 00165 Rome, Italy.
Sara SantarsieroDepartment of Otorhinolaryngology, Children's Hospital "Ospedale Pediatrico Bambino Gesù-IRCCS", 00165 Rome, Italy.
Giulia MariniDepartment of Otorhinolaryngology, Children's Hospital "Ospedale Pediatrico Bambino Gesù-IRCCS", 00165 Rome, Italy.
Fabio MajoDepartment of Cystic Fibrosis, Children's Hospital "Ospedale Pediatrico Bambino Gesù-IRCCS", 00165 Rome, Italy.
Marcello De VincentiisFaculty of Medicine and Surgery, University "Università Degli Studi Tor Vergata di Roma", 00133 Rome, Italy.
Giovanni CristalliDepartment of Otorhinolaryngology, Children's Hospital "Ospedale Pediatrico Bambino Gesù-IRCCS", 00165 Rome, Italy.
Maria Cristina ArtesaniDepartment of Allergology, Children's Hospital "Ospedale Pediatrico Bambino Gesù-IRCCS", 00165 Rome, Italy.
Alessandro Giovanni FiocchiDepartment of Allergology, Children's Hospital "Ospedale Pediatrico Bambino Gesù-IRCCS", 00165 Rome, Italy.
Bambino Gesù Children's Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasal polyps (NPs) are rarely reported in childhood and usually represent red flags for systemic diseases, such as cystic fibrosis (CF), primary ciliary dyskinesia (PCD) and immunodeficiencies. The European Position Paper released in 2020 (EPOS 2020) provided a detailed classification and defined the correct diagnostic and therapeutic approaches. We report a one-year experience of a multidisciplinary team, made up of otorhinolaryngologists, allergists, pediatricians, pneumologists and geneticists, with the aim of ensuring a personalized diagnostic and therapeutic management of the pathology. In 16 months of activity, 53 patients were admitted (25 children with chronic rhinosinusitis with polyposis and 28 with antro-choanal polyp). All patients underwent phenotypic and endo-typic assessment, using proper classification tools for nasal pathology (both endoscopic and radiological), as well as adequate cytological definition. An immuno-allergic evaluation was carried out. Pneumologists evaluated any lower airway respiratory disease. Genetic investigations concluded the diagnostic investigation. Our experience enhanced the complexity of children's NPs. A multidisciplinary assessment is mandatory for a targeted diagnostic and therapeutic pathway.

Indexed as

antro-choanal polypCFTR-related disorderchildrenchronic rhinosinusitisimmunodeficiencynasal polypsprimary ciliary dyskinesia

Identifiers

PMID37240876
PMCPMC10219557
OpenAlexW4366826506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.