Evidence map›Paper›PMID 37240762›Full record

ReviewLife (Basel, Switzerland)2023

Role of Extracellular Vesicles in Liver Diseases.

Viola Tamasi, Krisztina Németh, Miklós Csala

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Reprogramming macrophages to treat liver diseases.Hepatology (Baltimore, Md.) · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Characterizing Extracellular Vesicles from Biological Fluids.Journal of visualized experiments : JoVE · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Unveiling the cancer risk nexus of the steatotic liver.Trends in endocrinology and metabolism: TEM · 2024
    Review
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Viola TamasiDepartment of Molecular Biology, Semmelweis University, 1094 Budapest, Hungary.
Krisztina NémethDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0002-3825-2137
Miklós CsalaDepartment of Molecular Biology, Semmelweis University, 1094 Budapest, Hungary.ORCID 0000-0002-3829-4361
Semmelweis University · HU

Funding

EU's Horizon 2020 Research and Innovation Programme No. 739593, the program RRF-2.3.1-21-2022-00003National Research Centre TKP2021-EGA-23National Research, Development and Innovation Fund TKP2021-EGA-24VEKOP VEKOP-2.3.2-16-2016-000002, VEKOP-2.3.3-15-2017-00016
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are cell-derived membrane structures that are formed by budding from the plasma membrane or originate from the endosomal system. These microparticles (100 nm-100 µm) or nanoparticles (>100 nm) can transport complex cargos to other cells and, thus, provide communication and intercellular regulation. Various cells, such as hepatocytes, liver sinusoidal endothelial cells (LSECs) or hepatic stellate cells (HSCs), secrete and take up EVs in the healthy liver, and the amount, size and content of these vesicles are markedly altered under pathophysiological conditions. A comprehensive knowledge of the modified EV-related processes is very important, as they are of great value as biomarkers or therapeutic targets. In this review, we summarize the latest knowledge on hepatic EVs and the role they play in the homeostatic processes in the healthy liver. In addition, we discuss the characteristic changes of EVs and their potential exacerbating or ameliorating effects in certain liver diseases, such as non-alcoholic fatty liver disease (NAFLD), alcoholic fatty liver disease (AFLD), drug induced liver injury (DILI), autoimmune hepatitis (AIH), hepatocarcinoma (HCC) and viral hepatitis.

Indexed as

AFLDautoimmune hepatitisdrug-induced hepatitisextracellular vesicleshepatocarcinomahepatocytesliverNAFLDviral hepatitis

Identifiers

PMID37240762
PMCPMC10222904
OpenAlexW4367627034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.