Evidence map›Paper›PMID 37240686›Full record

ReviewJournal of clinical medicine2023

Pseudoexfoliation Syndrome-Clinical Characteristics of Most Common Cause of Secondary Glaucoma.

Martyna Tomczyk-Socha, Wojciech Tomczak, Weronika Winkler-Lach, Anna Turno-Kręcicka

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06946030 (The Relationship Between Ocular Pseudoexfoliation Syndrome and Carpal Tunnel Syndrome), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06946030 completednot on this mapstarted 2025, after this paper: background citation

The Relationship Between Ocular Pseudoexfoliation Syndrome and Carpal Tunnel Syndrome

TypeobservationalSponsorAnkara Training and Research HospitalRan2025 to 2026Enrolled159ConditionsPseudoexfoliation Syndrome, Carpal Tunnel Syndrome (CTS)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Pre-diagnostic plasma endogenous steroids and the risk of exfoliation glaucoma.medRxiv : the preprint server for health sciences · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Position of the ISTENT InjectJournal of clinical medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Martyna Tomczyk-SochaDepartment of Ophthalmology, Wroclaw Medical University, 50-367 Wrocław, Poland.
Wojciech TomczakLower Silesian Oncology Center, 53-413 Wroclaw, Poland.ORCID 0009-0006-1073-0797
Weronika Winkler-LachLower Silesian Oncology Center, 53-413 Wroclaw, Poland.
Anna Turno-KręcickaDepartment of Ophthalmology, Wroclaw Medical University, 50-367 Wrocław, Poland.
Lublin Oncology Center · PLWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudoexfoliation syndrome (XFS) is a condition in which excess material builds up not only in the structures of the anterior chamber but also throughout the body. The frequency of the syndrome varies significantly (0.3-18%) depending on the region and the method of examination. Environmental risk factors for XFS include a large number of sunny days, proximity to the equator, dietary factors such as higher consumption of coffee and tea, long-term alcohol consumption, exposure to UV, and outdoor work. The pathognomonic sign of XFS is the presence of white material on the lens capsule and other anterior chamber components. In addition, a characteristic Sampaolesi line can be observed during gonioscopy. Systemic alterations indicative of XFS have been observed in the extracellular matrix of the eyelid skin, the heart, lungs, liver, kidneys, gallbladder, meninges, and endothelium of the blood vessels. XFS is the most common cause of secondary open-angle glaucoma, which is called pseudoexfoliative glaucoma and is more severe than primary open-angle glaucoma. It is plausible that a combination of environmental factors and genetic alterations promotes the onset of pseudoexfoliation syndrome, which requires additional research.

Indexed as

clinical characteristicsenvironmental factorspseudoefoliation glaucomapseudoexfoliation syndrome

Identifiers

PMID37240686
PMCPMC10218815
OpenAlexW4377287712

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.