Evidence map›Paper›PMID 37240623›Full record

ReviewJournal of clinical medicine2023

Local Therapies for Hepatocellular Carcinoma and Role of MRI-Guided Adaptive Radiation Therapy.

Yirong Liu, Brian Chou, Amulya Yalamanchili, Sara N Lim, Laura A Dawson, Tarita O Thomas

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Stereotactic radiotherapy with Gamma Master SystemRadiation oncology (London, England) · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yirong LiuDepartment of Radiation Oncology, Northwestern Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-4019-6901
Brian ChouDepartment of Radiation Oncology, Loyola University Medical Center, Maywood, IL 60153, USA.ORCID 0000-0003-1836-3371
Amulya YalamanchiliDepartment of Radiation Oncology, Northwestern Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-7756-6497
Sara N LimDepartment of Radiation Oncology, Northwestern Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-3281-1900
Laura A DawsonDepartment of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON M5S 1A1, Canada.
Tarita O ThomasDepartment of Radiation Oncology, Northwestern Medicine, Chicago, IL 60611, USA.
Northwestern Medicine · USLoyola University Medical Center · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most common liver tumor, with a continually rising incidence. The curative treatment for HCC is surgical resection or liver transplantation; however, only a small portion of patients are eligible due to local tumor burden or underlying liver dysfunction. Most HCC patients receive nonsurgical liver-directed therapies (LDTs), including thermal ablation, transarterial chemoembolization (TACE), transarterial radioembolization (TARE), and external beam radiation therapy (EBRT). Stereotactic ablative body radiation (SABR) is a specific type of EBRT that can precisely deliver a high dose of radiation to ablate tumor cells using a small number of treatments (or fractions, typically 5 or less). With onboard MRI imaging, MRI-guided SABR can improve therapeutic dose while minimizing normal tissue exposure. In the current review, we discuss different LDTs and compare them with EBRT, specifically SABR. The emerging MRI-guided adaptive radiation therapy has been reviewed, highlighting its advantages and potential role in HCC management.

Indexed as

hepatocellular carcinoma (HCC)liver-directed therapies (LDTs)MRI-guided SABRstereotactic ablative body radiation (SABR)stereotactic MRI-guided on-table adaptive radiotherapy (SMART)transarterial radioembolization (TARE)

Identifiers

PMID37240623
PMCPMC10218854
OpenAlexW4377020821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.