Evidence map›Paper›PMID 37240475›Full record

ArticleJournal of clinical medicine2023

Differences in Selective Attention and Inhibitory Control in Patients with Major Depressive Disorder and Healthy Controls Who Do Not Engage in Sufficient Physical Activity.

Markus Gerber, Robyn Cody, Johannes Beck, Serge Brand, Lars Donath, Anne Eckert, Oliver Faude, Martin Hatzinger, Christian Imboden, Jan-Niklas Kreppke and 7 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Markus GerberDepartment for Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.ORCID 0000-0001-6140-8948
Robyn CodyDepartment for Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.
Johannes BeckPsychiatric Clinic Sonnenhalde, 4125 Riehen, Switzerland.
Serge BrandDepartment for Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.ORCID 0000-0003-2175-2765
Lars DonathDepartment of Intervention Research in Exercise Training, German Sport University Cologne, 50933 Cologne, Germany.
Anne EckertAdult Psychiatric Clinics (UPKE), University of Basel, 4002 Basel, Switzerland.ORCID 0000-0002-9341-3669
Oliver FaudeDepartment for Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.ORCID 0000-0002-2832-7780
Martin HatzingerPsychiatric Services Solothurn, University of Basel, 4503 Solothurn, Switzerland.
Christian ImbodenPrivate Clinic Wyss, 3053 Münchenbuchsee, Switzerland.ORCID 0000-0001-9912-0413
Jan-Niklas KreppkeDepartment for Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.ORCID 0000-0002-8187-920X
Undine E LangAdult Psychiatric Clinics (UPKE), University of Basel, 4002 Basel, Switzerland.ORCID 0000-0002-3585-6533
Sarah MansPrivate Clinic Wyss, 3053 Münchenbuchsee, Switzerland.
Thorsten MikoteitPsychiatric Services Solothurn, University of Basel, 4503 Solothurn, Switzerland.ORCID 0000-0003-2166-6330
Anja OswaldPsychiatric Clinic Sonnenhalde, 4125 Riehen, Switzerland.
Nina Schweinfurth-KeckAdult Psychiatric Clinics (UPKE), University of Basel, 4002 Basel, Switzerland.
Lukas ZahnerDepartment for Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.
Sebastian LudygaDepartment for Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.ORCID 0000-0002-3905-7894

Funding

Swiss National Science Foundation 321003B-179353
6 · The paper itself

Abstract

backgroundPatients with major depressive disorder (MDD) are characterized by neurocognitive impairments and show deficits in various cognitive performance indicators, including executive function. We examined whether sustained attention and inhibitory control differ between patients with MDD and healthy controls, and whether differences exist between patients with mild, moderate, and severe depression.

methodsClinical in-patients (

resultsPatients with MDD showed slower reaction times in both the oddball and flanker task, independent of the executive demands of the trial types. Younger participants achieved shorter reaction times in both inhibitory control tasks. After correcting for age, education, smoking, BMI, and nationality, only differences in reaction times in the oddball task were statistically significant. In contrast, reaction times were not sensitive to the symptom severity of depression.

conclusionOur results corroborate deficits in basic information processing and specific impairments in higher-order cognitive processes in MDD patients. As difficulties in executive function underlie problems in planning, initiating, and completing goal-directed activities, they may jeopardize in-patient treatment and contribute to the recurrent nature of depression.

Indexed as

Beck Depression Inventoryexecutive functionflanker taskinhibitory controlmajor depressionoddball taskPACINPAT trialsustained attentionsymptom severity

Identifiers

PMID37240475
PMCPMC10218814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.