Evidence map›Paper›PMID 37240427›Full record

ReviewInternational journal of molecular sciences2023

RNAi Technology: A New Path for the Research and Management of Obligate Biotrophic Phytopathogenic Fungi.

Isabel Padilla-Roji, Laura Ruiz-Jiménez, Nisrine Bakhat, Alejandra Vielba-Fernández, Alejandro Pérez-García, Dolores Fernández-Ortuño

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
10.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Challenges and Opportunities Arising from Host-International journal of molecular sciences · 2024
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Isabel Padilla-RojiDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.
Laura Ruiz-JiménezDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0003-2147-358X
Nisrine BakhatDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0009-0009-8304-8424
Alejandra Vielba-FernándezDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.
Alejandro Pérez-GarcíaDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0002-1065-0360
Dolores Fernández-OrtuñoDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0002-3134-3095
Consejo Superior de Investigaciones Científicas · ES

Funding

Agencia Estatal de Investigación (AEI) PID2019-107464RB-C21
6 · The paper itself

Abstract

Powdery mildew and rust fungi are major agricultural problems affecting many economically important crops and causing significant yield losses. These fungi are obligate biotrophic parasites that are completely dependent on their hosts for growth and reproduction. Biotrophy in these fungi is determined by the presence of haustoria, specialized fungal cells that are responsible for nutrient uptake and molecular dialogue with the host, a fact that undoubtedly complicates their study under laboratory conditions, especially in terms of genetic manipulation. RNA interference (RNAi) is the biological process of suppressing the expression of a target gene through double-stranded RNA that induces mRNA degradation. RNAi technology has revolutionized the study of these obligate biotrophic fungi by enabling the analysis of gene function in these fungal. More importantly, RNAi technology has opened new perspectives for the management of powdery mildew and rust diseases, first through the stable expression of RNAi constructs in transgenic plants and, more recently, through the non-transgenic approach called spray-induced gene silencing (SIGS). In this review, the impact of RNAi technology on the research and management of powdery mildew and rust fungi will be addressed.

Indexed as

BasidiomycotaPlant DiseasesErysipheGene SilencingRNA, Double-StrandedRNA InterferenceRNA, Double-StrandedATM-HIGSdsRNAHIGSpowdery mildewRNA interferencerustSIGStransgenic plantsVIGS

Identifiers

PMID37240427
PMCPMC10219382
OpenAlexW4378078426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.