Evidence map›Paper›PMID 37240273›Full record

ArticleInternational journal of molecular sciences2023

Effect of Secretion Efficiency of Mutant KRAS Neoantigen by

Nur Aqlili Riana Alias, Winfrey Pui Yee Hoo, Pui Yan Siak, Siti Sarah Othman, Noorjahan Banu Mohammed Alitheen, Lionel Lian Aun In, Raha Abdul Rahim, Adelene Ai-Lian Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Pharmaceutics · 2026
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nur Aqlili Riana AliasDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0002-3741-7411
Winfrey Pui Yee HooDepartment of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Pui Yan SiakFaculty of Medicine and Health Sciences, UCSI University, Bandar Springhill, Port Dickson 71010, Malaysia.
Siti Sarah OthmanDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0001-5802-6359
Noorjahan Banu Mohammed AlitheenDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Lionel Lian Aun InDepartment of Biotechnology, Faculty of Applied Sciences, UCSI University Kuala Lumpur, Cheras 56000, Malaysia.ORCID 0000-0001-7182-112X
Raha Abdul RahimDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Adelene Ai-Lian SongDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0002-5413-3314
Universiti Putra Malaysia · MYUCSI University · MYAustralian Regenerative Medicine Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is often caused by mutations in the KRAS oncogene, making KRAS neoantigens a promising vaccine candidate for immunotherapy. Secreting KRAS antigens using live Generally Recognized as Safe (GRAS) vaccine delivery hosts such as

Indexed as

Colorectal NeoplasmsLactococcus lactisVaccinesAnimalsAntigensImmunity, MucosalImmunoglobulin AMiceProtein Sorting SignalsProto-Oncogene Proteins p21(ras)AntigensImmunoglobulin AProtein Sorting SignalsProto-Oncogene Proteins p21(ras)Vaccinescolorectal cancerimmunotherapyLactococcus lactismucosal vaccine deliverymutant KRAS antigensecretionsignal peptideSPK1

Identifiers

PMID37240273
PMCPMC10219268
OpenAlexW4377103716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.