Evidence map›Paper›PMID 37240179›Full record

ReviewInternational journal of molecular sciences2023

The Sts Proteins: Modulators of Host Immunity.

Anika Zaman, Jarrod B French, Nick Carpino

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Anika ZamanGraduate Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, NY 11794, USA.
Jarrod B FrenchHormel Institute, University of Minnesota, 801 16th Ave NE, Austin, MN 55912, USA.ORCID 0000-0002-6762-1309
Nick CarpinoDepartment of Microbiology and Immunology, Stony Brook University, Stony Brook, NY 11794, USA.
Stony Brook University · USUniversity of Minnesota · US

Funding

Optimizing the immune response by targeting the Sts enzymesR01AI141592 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI CARPINO, NICHOLAS A, FRENCH, JARROD B · 2019 to 2022
$2.4M
Integrated Acoustic Transfer System for HTS Library ManagementS10OD025279 · OD · SCRIPPS FLORIDA · PI SCAMPAVIA, LOUIS DANIEL · 2018 to 2018
$624k
Tandem Multi-modal Plate Readers for a High Throughput Screening platformS10OD030330 · OD · UNIVERSITY OF FLORIDA · PI SCAMPAVIA, LOUIS DANIEL · 2021 to 2021
$600k
HTS Drug  Discovery DispensersS10OD026857 · OD · SCRIPPS FLORIDA · PI SCAMPAVIA, LOUIS DANIEL · 2019 to 2019
$452k
Function of the Sts protein phosphodiesterase domainR21AI156238 · NIAID · UNIVERSITY OF MINNESOTA · PI FRENCH, JARROD B · 2021 to 2022
$445k
NIAID NIH HHS R01 AI141592NIAID NIH HHS R21 AI156238NIH HHS R01AI141592NIH HHS R21AI156238NIH HHS S10 OD025279NIH HHS S10 OD026857NIH HHS S10 OD030330
6 · The paper itself

Abstract

The suppressor of TCR signaling (Sts) proteins, Sts-1 and Sts-2, are a pair of closely related signaling molecules that belong to the histidine phosphatase (HP) family of enzymes by virtue of an evolutionarily conserved C-terminal phosphatase domain. HPs derive their name from a conserved histidine that is important for catalytic activity and the current evidence indicates that the Sts HP domain plays a critical functional role. Sts-1

Indexed as

HistidineProtein Tyrosine PhosphatasesAnimalsMiceReceptors, Antigen, T-CellSignal TransductionT-LymphocytesHistidineProtein Tyrosine PhosphatasesReceptors, Antigen, T-CellCandida albicansFrancisella tularensishistidine phosphatasephosphodiesteraseSts-1Sts-2

Identifiers

PMID37240179
PMCPMC10218301
OpenAlexW4377043156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.