Evidence map›Paper›PMID 37240050›Full record

ArticleInternational journal of molecular sciences2023

Simple Coumarins from

Jarosław Widelski, Natalia Kasica, Monika Maciąg, Simon Vlad Luca, Barbara Budzyńska, Dafina Fondai, Piotr Podlasz, Krystyna Skalicka-Woźniak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. ACS omega · 2026
    Article
  2. The Zebrafish Model in Animal and Human Health Research.International journal of molecular sciences · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Jarosław WidelskiMedicinal Plant Unit, Department of Pharmacognosy, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0003-3154-9138
Natalia KasicaDepartment of Animal Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-0242-2587
Monika MaciągIndependent Laboratory of Behavioral Studies, Medical University of Lublin, 20-093 Lublin, Poland.
Simon Vlad LucaBiothermodynamics, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.ORCID 0000-0003-0904-0060
Barbara BudzyńskaIndependent Laboratory of Behavioral Studies, Medical University of Lublin, 20-093 Lublin, Poland.
Dafina FondaiDepartment of Pharmacy, Faculty of Medicine, University of Prishtina, 10000 Prishtina, Kosovo.
Piotr PodlaszDepartment of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-9162-5449
Krystyna Skalicka-WoźniakDepartment of Chemistry of Natural Products, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-9313-5929
Medical University of Lublin · PLUniversity of Warmia and Mazury in Olsztyn · PLGrigore T. Popa University of Medicine and Pharmacy · ROUniversity of Prishtina · XK

Funding

National Science Center 2017/25/N/NZ7/01899
6 · The paper itself

Abstract

Anxiety is one of the most common central nervous system disorders, affecting at least one-quarter of the worldwide population. The medications routinely used for the treatment of anxiety (mainly benzodiazepines) are a cause of addiction and are characterized by many undesirable side effects. Thus, there is an important and urgent need for screening and finding novel drug candidates that can be used in the prevention or treatment of anxiety. Simple coumarins usually do not show side effects, or these effects are much lower than in the case of synthetic drugs acting on the central nervous system (CNS). This study aimed to evaluate the anxiolytic activity of three simple coumarins from

Indexed as

Anti-Anxiety AgentsAnimalsAnxietyCoumarinsFruitGene ExpressionIsobutyratesZebrafishAnti-Anxiety AgentsCoumarinsIsobutyratescentral nervous systemDanio reriohydroxycoumarinsofficinalinPeucedanum ruthenicumstenocarpin isobutyrate

Identifiers

PMID37240050
PMCPMC10218424
OpenAlexW4376614870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.