Evidence map›Paper›PMID 37240033›Full record

ArticleInternational journal of molecular sciences2023

Griseofulvin Inhibits Root Growth by Targeting Microtubule-Associated Proteins Rather Tubulins in

Yanjing Guo, Jingjing Li, Jiale Shi, Liru Mi, Jing Zhang, Su Han, Wei Liu, Dan Cheng, Sheng Qiang, Hazem M Kalaji and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yanjing GuoWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Jingjing LiWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Jiale ShiWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Liru MiWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Jing ZhangWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Su HanWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Wei LiuWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Dan ChengWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Sheng QiangWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0003-1183-9453
Hazem M KalajiInstitute of Technology and Life Sciences; National Research Institute, Falenty, Al. Hrabska 3, 05-090 Raszyn, Poland.ORCID 0000-0002-3833-4917
Shiguo ChenWeed Research Laboratory, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-8762-1373
Nanjing Agricultural University · CNWarsaw University of Life Sciences · PL

Funding

Jiangsu Agriculture Science and Technology Innovation Fund CX(21)3093National Key Research and Development Program 2021YFD1700100 and 2017YFD0201300
6 · The paper itself

Abstract

Griseofulvin was considered an effective agent for cancer therapy in past decades. Although the negative effects of griseofulvin on microtubule stability are known, the exact target and mechanism of action in plants remain unclear. Here, we used trifluralin, a well-known herbicide targeting microtubules, as a reference and revealed the differences in root tip morphology, reactive oxygen species production (ROS), microtubule dynamics, and transcriptome analysis between

Indexed as

ArabidopsisArabidopsis ProteinsGriseofulvinMicrotubule-Associated ProteinsMicrotubulesPlant RootsReactive Oxygen SpeciesTrifluralinTubulinArabidopsis ProteinsGriseofulvinMicrotubule-Associated ProteinsReactive Oxygen SpeciesTrifluralinTubulinmicrotubulemycotoxinplant hormonereactive oxygen species (ROS)transcriptome analysis

Identifiers

PMID37240033
PMCPMC10217847
OpenAlexW4378516397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.