Evidence map›Paper›PMID 37240005›Full record

ArticleInternational journal of molecular sciences2023

Yeast Chaperone Hsp70-Ssb Modulates a Variety of Protein-Based Heritable Elements.

Lina M Jay-Garcia, Joseph L Cornell, Rebecca L Howie, Quincy L Faber, Abigail Salas, Tatiana A Chernova, Yury O Chernoff

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Anti-Prion Systems in Saccharomyces cerevisiae.Journal of neurochemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lina M Jay-GarciaSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Joseph L CornellSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Rebecca L HowieSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Quincy L FaberSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Abigail SalasSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Tatiana A ChernovaDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0003-1966-0159
Yury O ChernoffSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.ORCID 0000-0002-8934-9051
Georgia Institute of Technology · USEmory University · US

Funding

National Science Foundation 1817976
6 · The paper itself

Abstract

Prions are transmissible self-perpetuating protein isoforms associated with diseases and heritable traits. Yeast prions and non-transmissible protein aggregates (mnemons) are frequently based on cross-β ordered fibrous aggregates (amyloids). The formation and propagation of yeast prions are controlled by chaperone machinery. Ribosome-associated chaperone Hsp70-Ssb is known (and confirmed here) to modulate formation and propagation of the prion form of the Sup35 protein [

Indexed as

GTP-Binding Protein gamma SubunitsPrionsSaccharomyces cerevisiae ProteinsGlutathione PeroxidaseHSP70 Heat-Shock ProteinsMolecular ChaperonesPeptide Termination FactorsSaccharomyces cerevisiaeGlutathione PeroxidaseGTP-Binding Protein gamma SubunitsHSP70 Heat-Shock ProteinsMolecular ChaperonesPeptide Termination FactorsPrionsSaccharomyces cerevisiae ProteinsSTE18 protein, S cerevisiaeSUP35 protein, S cerevisiaeURE2 protein, S cerevisiaeZUO1 protein, S cerevisiaeamyloidGγheat shockLsb2mnemonprionRACSsbUre2yeast

Identifiers

PMID37240005
PMCPMC10218661
OpenAlexW4376275309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.