Evidence map›Paper›PMID 37239967›Full record

ReviewInternational journal of molecular sciences2023

CRISPR-Based Genome Editing Tools: An Accelerator in Crop Breeding for a Changing Future.

Fangning Zhang, Ting Xiang Neik, William J W Thomas, Jacqueline Batley

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fangning ZhangCollege of Life Sciences, Shandong Normal University, Jinan 250014, China.
Ting Xiang NeikSchool of Biosciences, University of Nottingham Malaysia, Semenyih 43500, Malaysia.
William J W ThomasSchool of Biological Sciences, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0002-5147-8704
Jacqueline BatleySchool of Biological Sciences, Institute of Agriculture, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0002-5391-5824

Funding

Australian Research Council DP200100762Australian Research Council DP210100296
6 · The paper itself

Abstract

Genome editing is an important strategy to maintain global food security and achieve sustainable agricultural development. Among all genome editing tools, CRISPR-Cas is currently the most prevalent and offers the most promise. In this review, we summarize the development of CRISPR-Cas systems, outline their classification and distinctive features, delineate their natural mechanisms in plant genome editing and exemplify the applications in plant research. Both classical and recently discovered CRISPR-Cas systems are included, detailing the class, type, structures and functions of each. We conclude by highlighting the challenges that come with CRISPR-Cas and offer suggestions on how to tackle them. We believe the gene editing toolbox will be greatly enriched, providing new avenues for a more efficient and precise breeding of climate-resilient crops.

Indexed as

Gene EditingPlant BreedingCRISPR-Cas SystemsCrops, AgriculturalGenome, PlantCRISPR-Cas systemscrop breedingplant genome editing

Identifiers

PMID37239967
PMCPMC10218198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.