Evidence map›Paper›PMID 37239962›Full record

ArticleInternational journal of molecular sciences2023

Structure of

Isabell Berneburg, Michaela Stumpf, Ann-Sophie Velten, Stefan Rahlfs, Jude Przyborski, Katja Becker, Karin Fritz-Wolf

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. EXCLI journal · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Isabell BerneburgBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, 35392 Giessen, Germany.ORCID 0000-0003-3280-7311
Michaela StumpfBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, 35392 Giessen, Germany.
Ann-Sophie VeltenBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, 35392 Giessen, Germany.
Stefan RahlfsBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, 35392 Giessen, Germany.ORCID 0000-0003-4412-9925
Jude PrzyborskiBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, 35392 Giessen, Germany.
Katja BeckerBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, 35392 Giessen, Germany.
Karin Fritz-WolfBiochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, 35392 Giessen, Germany.ORCID 0000-0002-4422-6795
Justus-Liebig-Universität Gießen · DE

Funding

Loewe Center Druid (Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases) Project B3/E3
6 · The paper itself

Abstract

As unicellular parasites are highly dependent on NADPH as a source for reducing equivalents, the main NADPH-producing enzymes glucose 6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD) of the pentose phosphate pathway are considered promising antitrypanosomatid drug targets. Here we present the biochemical characterization and crystal structure of

Indexed as

Leishmania donovaniLeishmaniasisAuranofinGlucosephosphate DehydrogenaseGoldHumansNADPPhosphinesPhosphogluconate DehydrogenaseAuranofinGlucosephosphate DehydrogenaseGoldNADPphosphinePhosphinesPhosphogluconate Dehydrogenase6-phosphogluconate dehydrogenaseauranofinleishmaniasispentose phosphate pathwayphosphine gold(I)-complexes

Identifiers

PMID37239962
PMCPMC10217883
OpenAlexW4376279040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.