Evidence map›Paper›PMID 37239913›Full record

ArticleInternational journal of molecular sciences2023

6-Polyaminosteroid Squalamine Analogues Display Antibacterial Activity against Resistant Pathogens.

Delphine Vergoz, Flore Nilly, Florie Desriac, Magalie Barreau, Antoine Géry, Charlie Lepetit, François Sichel, Katy Jeannot, Jean-Christophe Giard, David Garon and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Delphine VergozPolymers, Biopolymers, Surfaces Laboratory, University of Rouen Normandie, INSA Rouen, CNRS, UMR 6270, 76000 Rouen, France.
Flore NillyCommunication Bactérienne et Stratégies Anti-Infectieuses, University of Rouen Normandie, CBSA, 27000 Evreux, France.
Florie DesriacCommunication Bactérienne et Stratégies Anti-Infectieuses, UNICAEN, Normandie University, UR4312, CBSA, 14032 Caen, France.
Magalie BarreauCommunication Bactérienne et Stratégies Anti-Infectieuses, University of Rouen Normandie, CBSA, 27000 Evreux, France.
Antoine GéryUNICAEN, Normandie University, ABTE UR4651 and Centre François Baclesse, 14032 Caen, France.ORCID 0000-0002-3144-9260
Charlie LepetitUNICAEN, Normandie University, ABTE UR4651 and Centre François Baclesse, 14032 Caen, France.
François SichelUNICAEN, Normandie University, ABTE UR4651 and Centre François Baclesse, 14032 Caen, France.ORCID 0000-0002-4094-7739
Katy JeannotUMR 6249 Chrono-Environnement, CNRS-Université de Bourgogne/Franche-Comté, 25000 Besançon, France.ORCID 0000-0002-4634-8550
Jean-Christophe GiardUNICAEN, University of Rouen Normandie, INSERM, DYNAMICURE UMR 1311 F, 14000 Caen, France.
David GaronUNICAEN, Normandie University, ABTE UR4651 and Centre François Baclesse, 14032 Caen, France.ORCID 0000-0003-3545-6641
Sylvie ChevalierCommunication Bactérienne et Stratégies Anti-Infectieuses, University of Rouen Normandie, CBSA, 27000 Evreux, France.ORCID 0000-0001-6489-438X
Cécile MullerCommunication Bactérienne et Stratégies Anti-Infectieuses, UNICAEN, Normandie University, UR4312, CBSA, 14032 Caen, France.ORCID 0000-0003-3078-1920
Emmanuelle DéPolymers, Biopolymers, Surfaces Laboratory, University of Rouen Normandie, INSA Rouen, CNRS, UMR 6270, 76000 Rouen, France.ORCID 0000-0002-9564-1649
Jean Michel BrunelAix Marseille University, INSERM, SSA, MCT, 13385 Marseille, France.ORCID 0000-0002-9355-8980
Normandie Université · FRCentre National de la Recherche Scientifique · FRCommunication Bactérienne et Stratégie Anti-infectieusesInserm · FR

Funding

European Union in the framework of the ERDF-ESF program 2014-2020 RN3A. RN3A
6 · The paper itself

Abstract

A series of 6-polyaminosteroid analogues of squalamine were synthesized with moderate to good yields and evaluated for their

Indexed as

Methicillin-Resistant Staphylococcus aureusAnti-Bacterial AgentsCholestanolsGram-Negative BacteriaGram-Positive BacteriaMicrobial Sensitivity TestsVancomycinAnti-Bacterial AgentsCholestanolssqualamineVancomycinAcinetobacter baumanniiaminosteroid derivativesantimicrobial activitiesEnterococcus faeciumpolyaminePseudomonas aeruginosaStaphylococcus aureus

Identifiers

PMID37239913
PMCPMC10218190
OpenAlexW4376138608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.