Evidence map›Paper›PMID 37239898›Full record

ArticleInternational journal of molecular sciences2023

Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort.

Orsolya Pipek, Donát Alpár, Orsolya Rusz, Csaba Bödör, Zoltán Udvarnoki, Anna Medgyes-Horváth, István Csabai, Zoltán Szállási, Lilla Madaras, Zsuzsanna Kahán and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Orsolya PipekDepartment of Physics of Complex Systems, Institute of Physics, Eötvös Loránd University, 1117 Budapest, Hungary.ORCID 0000-0001-8109-0340
Donát AlpárHCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0002-2638-5418
Orsolya RuszDepartment of Pathology, Forensic and Insurance Medicine, SE NAP, Brain Metastasis Research Group, Semmelweis University, 1091 Budapest, Hungary.
Csaba BödörHCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary.
Zoltán UdvarnokiDepartment of Physics of Complex Systems, Institute of Physics, Eötvös Loránd University, 1117 Budapest, Hungary.ORCID 0000-0001-7086-235X
Anna Medgyes-HorváthDepartment of Physics of Complex Systems, Institute of Physics, Eötvös Loránd University, 1117 Budapest, Hungary.ORCID 0000-0003-4435-5797
István CsabaiDepartment of Physics of Complex Systems, Institute of Physics, Eötvös Loránd University, 1117 Budapest, Hungary.
Zoltán SzállásiDepartment of Pathology, Forensic and Insurance Medicine, SE NAP, Brain Metastasis Research Group, Semmelweis University, 1091 Budapest, Hungary.
Lilla MadarasDepartment of Pathology, Forensic and Insurance Medicine, Semmelweis University, 1091 Budapest, Hungary.
Zsuzsanna KahánDepartment of Oncotherapy, University of Szeged, 6720 Szeged, Hungary.
Gábor CserniDepartment of Pathology, Albert Szent-Györgyi Medical Centre, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0003-1344-7744
Bence KőváriDepartment of Pathology, Albert Szent-Györgyi Medical Centre, University of Szeged, 6720 Szeged, Hungary.
Janina KulkaDepartment of Pathology, Forensic and Insurance Medicine, Semmelweis University, 1091 Budapest, Hungary.ORCID 0000-0001-6498-5943
Anna Mária TőkésDepartment of Pathology, Forensic and Insurance Medicine, Semmelweis University, 1091 Budapest, Hungary.
Semmelweis University · HUEötvös Loránd University · HUUniversity of Szeged · HU

Funding

National Research, Development and Innovation Office NVKP_16-1-2016-0004 grant
6 · The paper itself

Abstract

A limited number of studies have focused on the mutational landscape of breast cancer in different ethnic populations within Europe and compared the data with other ethnic groups and databases. We performed whole-genome sequencing of 63 samples from 29 Hungarian breast cancer patients. We validated a subset of the identified variants at the DNA level using the Illumina TruSight Oncology (TSO) 500 assay. Canonical breast-cancer-associated genes with pathogenic germline mutations were

Indexed as

Breast NeoplasmsDNA Copy Number VariationsFemaleGenetic Predisposition to DiseaseGenomicsGerm-Line MutationHumansHungaryMutationbreast cancergermlinemutationsomaticwhole-genome sequencing

Identifiers

PMID37239898
PMCPMC10218458
OpenAlexW4376138662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.