Evidence map›Paper›PMID 37239830›Full record

ArticleInternational journal of molecular sciences2023

Light-Up Split Broccoli Aptamer as a Versatile Tool for RNA Assembly Monitoring in Cell-Free TX-TL Systems, Hybrid RNA/DNA Origami Tagging and DNA Biosensing.

Emanuela Torelli, Ben Shirt-Ediss, Silvia A Navarro, Marisa Manzano, Priya Vizzini, Natalio Krasnogor

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Aptamers: Functional-Structural Studies and Biomedical Applications 2.0.International journal of molecular sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emanuela TorelliInterdisciplinary Computing and Complex BioSystems (ICOS), Centre for Synthetic Biology and Bioeconomy (CSBB), Newcastle University, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0002-3313-1088
Ben Shirt-EdissInterdisciplinary Computing and Complex BioSystems (ICOS), Centre for Synthetic Biology and Bioeconomy (CSBB), Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
Silvia A NavarroInterdisciplinary Computing and Complex BioSystems (ICOS), Centre for Synthetic Biology and Bioeconomy (CSBB), Newcastle University, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0001-9290-1583
Marisa ManzanoDipartimento di Scienze AgroAlimentari, Ambientali e Animali, Università degli Studi di Udine, 33100 Udine, Italy.ORCID 0000-0002-3543-6141
Priya VizziniDipartimento di Scienze AgroAlimentari, Ambientali e Animali, Università degli Studi di Udine, 33100 Udine, Italy.ORCID 0000-0002-4596-5194
Natalio KrasnogorInterdisciplinary Computing and Complex BioSystems (ICOS), Centre for Synthetic Biology and Bioeconomy (CSBB), Newcastle University, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0002-2651-4320

Funding

EPSRC EP/N031962/1European Union's Horizon 2020 research and innovation programme 899833Krasnogor is supported by the Royal Academy of Engineering under the Chairs in Emerging Technologies Scheme nd
6 · The paper itself

Abstract

Binary light-up aptamers are intriguing and emerging tools with potential in different fields. Herein, we demonstrate the versatility of a split Broccoli aptamer system able to turn on the fluorescence signal only in the presence of a complementary sequence. First, an RNA three-way junction harbouring the split system is assembled in an

Indexed as

Aptamers, NucleotideBrassicaNanostructuresDNAEscherichia coliNucleic Acid ConformationRNAAptamers, NucleotideDNARNACampylobacter spp.cell-free TX-TL systemhybrid RNA/DNA origamilight-up split Broccoli aptamerRNA self-assembly monitoringtarget DNA detection

Identifiers

PMID37239830
PMCPMC10218337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.