Evidence map›Paper›PMID 37239469›Full record

ArticleGenes2023

Forensic Implications of the Discrepancies Caused between NGS and CE Results by New Microvariant Allele at Penta E Microsatellite.

Balázs Kocsis, Norbert Mátrai, Balázs Egyed

Abstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Balázs KocsisDepartment of Genetics, Hungarian Institute for Forensic Sciences, 1087 Budapest, Hungary.
Norbert MátraiDepartment of Genetics, Hungarian Institute for Forensic Sciences, 1087 Budapest, Hungary.ORCID 0000-0003-0962-6205
Balázs EgyedDepartment of Genetics, ELTE Eötvös Loránd University, 1117 Budapest, Hungary.ORCID 0000-0003-3960-2052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Examination of STR markers using the MPS technology is becoming more common in forensic genetics, but scientists still have insufficient experience in dealing with ambiguous results. However, it is always essential to resolve discordant data if we want to use the technology as an accredited method in routine forensic casework. During the internal laboratory validation of the Precision ID GlobalFiler NGS STR Panel v2 kit, we observed two discrepant genotypes at Penta E locus compared to the previous capillary electrophoresis results. Each NGS software that we applied (i.e., Converge, STRaitRazor and IGV) returned the same 12,14 and 12,16 genotypes in the two samples, respectively, instead of the 11.3,14 and 11.3,16 genotypes previously observed with CE (

Indexed as

DNA FingerprintingRubiaceaeAllelesHigh-Throughput Nucleotide SequencingMicrosatellite Repeatsforensicsgenotype discrepancymicroallele variantnext generation sequencingPenta E microsatellitePrecision ID GlobalFiler NGS STR Panel v2

Identifiers

PMID37239469
PMCPMC10218238

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.