Evidence map›Paper›PMID 37239426›Full record

ArticleGenes2023

Germline JAK2 E846D Substitution as the Cause of Erythrocytosis?

Nada Maaziz, Céline Garrec, Fabrice Airaud, Victor Bobée, Nathalie Contentin, Emilie Cayssials, Antoine Rimbert, Bernard Aral, Stéphane Bézieau, Betty Gardie and 1 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. How Genomic and Structural Context Could Shape JAK-STAT Variant Pathogenicity.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Nada MaazizLaboratoire de Génétique Chromosomique et Moléculaire, Pôle Biologie, CHU de Dijon, 21000 Dijon, France.
Céline GarrecService de Génétique Médicale, CHU de Nantes, 44000 Nantes, France.
Fabrice AiraudService de Génétique Médicale, CHU de Nantes, 44000 Nantes, France.
Victor BobéeService d'Hématologie Biologique, CHU de Rouen, 76000 Rouen, France.
Nathalie ContentinService d'Hématologie, Centre Henri Becquerel, 76000 Rouen, France.
Emilie CayssialsService d'Oncologie Hématologique, CHU de Poitiers, 86000 Poitiers, France.
Antoine Rimbertl'Institut du Thorax, INSERM, Nantes Université, CHU Nantes, 44300 Nantes, France.ORCID 0000-0002-2971-4926
Bernard AralLaboratoire de Génétique Chromosomique et Moléculaire, Pôle Biologie, CHU de Dijon, 21000 Dijon, France.
Stéphane BézieauService de Génétique Médicale, CHU de Nantes, 44000 Nantes, France.ORCID 0000-0003-0095-1319
Betty Gardiel'Institut du Thorax, INSERM, Nantes Université, CHU Nantes, 44300 Nantes, France.
François GirodonLaboratory of Excellence GR-Ex, Imagine Institute, 75015 Paris, France.ORCID 0000-0003-3151-1068
Inserm · FRCentre Hospitalier Universitaire de Nantes · FRCHU Dijon Bourgogne · FRCentre Henri BecquerelCentre Hospitalier Universitaire de Poitiers · FRCentre Hospitalier Universitaire de Rouen · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery in 2005 of the

Indexed as

PolycythemiaPolycythemia VeraCohort StudiesHematocritHumansJanus Kinase 2JAK2 protein, humanJanus Kinase 2erythrocytosisfamilial erythrocytosisgermline mutationJAK2 mutation

Identifiers

PMID37239426
PMCPMC10217867
OpenAlexW4378515375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.