Evidence map›Paper›PMID 37239325›Full record

ArticleGenes2023

Hepatic Transcriptomics Reveals Reduced Lipogenesis in High-Salt Diet Mice.

Jing Xu, Fei Mao, Yan Lu, Tiemin Liu, Xiaoying Li, Yao Li

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jing XuDepartment of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai 200032, China.ORCID 0000-0002-2758-5008
Fei MaoDepartment of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Yan LuInstitute of Metabolism and Regenerative Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Tiemin LiuSchool of Life Sciences, Fudan University, Shanghai 200032, China.
Xiaoying LiDepartment of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Yao LiDepartment of Laboratory Animal Science, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.
Sun Yat-sen University · CNShanghai Jiao Tong University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been demonstrated that a high salt diet (HSD) increases the risk of cardiovascular disease and metabolic dysfunction. In particular, the impact and molecular mechanisms of long-term HSD on hepatic metabolism remain largely unknown. To identify differentially expressed genes (DEGs) affecting the metabolism of liver tissues from HSD and control groups, a transcriptome analysis of liver tissues was performed in this study. As a result of the transcriptome analysis, the expression of genes related to lipid and steroid biosynthesis (such as

Indexed as

LipogenesisTranscriptomeAnimalsDietGene Expression ProfilingLipidsLiverMiceSteroidsLipidsSteroidsfatty acid profilehigh-salt dietlivermetabolismtranscriptomics

Identifiers

PMID37239325
PMCPMC10218062
OpenAlexW4366826075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.